Macular degeneration: recent advances and therapeutic opportunities

A Rattner, J Nathans - Nature Reviews Neuroscience, 2006 - nature.com
… , and its progressive dysfunction due to macular degeneration is the leading cause of visual
… in understanding the pathophysiology of macular degeneration and the implications of this …

Mechanisms of age‐related macular degeneration and therapeutic opportunities

M van Lookeren Campagne, J LeCouter… - The Journal of …, 2014 - Wiley Online Library
… Age-related macular degeneration (AMD) is a progressive degenerative disease of the
macula, an area in the retina responsible for visual acuity and colour vision (Figure 1). As its …

Current and emerging therapies for the treatment of age-related macular degeneration

MV Emerson, AK Lauer - Clinical ophthalmology, 2008 - Taylor & Francis
… Age-related macular degeneration (AMD) is the leading cause of vision loss in the
industrialized world. In the last few decades, the mainstay of treatment for choroidal …

[HTML][HTML] Therapeutic approaches for age-related macular degeneration

RM Galindo-Camacho, C Blanco-Llamero… - International journal of …, 2022 - mdpi.com
… In advanced age-related macular degeneration in only one eye, AREDS 2 may slow … of
macular degeneration in the other eye. If the patient already has advanced macular degeneration

Current and future therapies for age-related macular degeneration

J Beutel, M Rudolf, S Grisanti - Expert Opinion on Emerging Drugs, 2009 - Taylor & Francis
… Background: Age-related macular degeneration is the leading … Objective: In this article
we review current therapeutictherapies for neovascular AMD-like photodynamic therapy

Genetic studies of age-related macular degeneration: lessons, challenges, and opportunities for disease management

RR Priya, EY Chew, A Swaroop - Ophthalmology, 2012 - Elsevier
… Because Mendelian forms of macular degenerative diseases exhibit similar clinical
characteristics, the underlying genes have been investigated as candidates for conferring genetic …

[HTML][HTML] Age related macular degeneration–challenge for future: pathogenesis and new perspectives for the treatment

K Michalska-Małecka, A Kabiesz, M Nowak… - European Geriatric …, 2015 - Elsevier
… The authors presents the review of the literature concerning the pathogenesis, classification,
risk factors as well as perspectives for the treatment of age-related macular degeneration (…

Antibody therapies and their challenges in the treatment of age-related macular degeneration

C Volz, D Pauly - European Journal of Pharmaceutics and …, 2015 - Elsevier
… age-related macular degeneration (AMD) exposed to more than 30 injections is an unexpected
success that motivates further development of intra-ocular antibody therapeutics to treat …

Present and possible therapies for age‐related macular degeneration

M Khan, K Agarwal, M Loutfi… - International Scholarly …, 2014 - Wiley Online Library
… disorder characterized by changes occurring within the macula reflective of the ageing process.
… of therapies available for AMD and discuss the additional role of further novel therapies

New therapeutic targets in atrophic age-related macular degeneration

K Petrukhin - Expert Opinion on Therapeutic Targets, 2007 - Taylor & Francis
… Age-related macular degeneration (AMD) is the leading cause of blindness in developed
countries. There is no effective treatment for the most prevalent atrophic (dry) form of AMD. …