[HTML][HTML] Targeting macroautophagy as a therapeutic opportunity to treat Parkinson's disease
I Sanchez-Mirasierra, S Ghimire… - Frontiers in Cell and …, 2022 - frontiersin.org
… , therapeutics regulating the autophagy pathway might play an important role controlling the
disease … In this review, we highlight potential therapeutic opportunities involved in different …
disease … In this review, we highlight potential therapeutic opportunities involved in different …
Old and new challenges in Parkinson's disease therapeutics
AO Pires, FG Teixeira, B Mendes-Pinheiro… - Progress in …, 2017 - Elsevier
… Parkinson's disease (PD) is a neurodegenerative disorder characterized by the … status of
gene therapy for PD treatment will also be provided. All the therapeutic approaches outlined in …
gene therapy for PD treatment will also be provided. All the therapeutic approaches outlined in …
Technology in Parkinson's disease: challenges and opportunities
… use of body-fixed sensors in Parkinson disease. The intellectual property rights for this …
disease or aids in testing or delivering a therapy. The use of measurements to improve therapy is …
disease or aids in testing or delivering a therapy. The use of measurements to improve therapy is …
Therapeutic prospects for Parkinson disease
CW Olanow, AHV Schapira - Annals of neurology, 2013 - Wiley Online Library
… This schema offers several novel opportunities to provide a neuroprotective therapy for
Parkinson disease including: (1) agents that prevent misfolding or promote refolding of proteins; (…
Parkinson disease including: (1) agents that prevent misfolding or promote refolding of proteins; (…
Neuroprotective potential of cinnamon and its metabolites in Parkinson's disease: Mechanistic insights, limitations, and novel therapeutic opportunities
E Angelopoulou, YN Paudel, C Piperi… - Journal of biochemical …, 2021 - Wiley Online Library
… Herein, we discuss recent evidence on the novel therapeutic opportunities of this
phytochemical against PD, indicating additional mechanistic aspects that should be explored, and …
phytochemical against PD, indicating additional mechanistic aspects that should be explored, and …
[PDF][PDF] Early treatment of Parkinson's disease: opportunities for managed care
DL Murman - American Journal of Managed Care, 2012 - ajmc.s3.amazonaws.com
… in addition to pharmacological therapies, nonpharmacological therapies such as physical
therapy (PT) and exercise also offer opportunities for improving patient status in Pd. While PT …
therapy (PT) and exercise also offer opportunities for improving patient status in Pd. While PT …
Progress towards therapies for disease modification in Parkinson's disease
N Vijiaratnam, T Simuni, O Bandmann… - The Lancet …, 2021 - thelancet.com
… The development of interventions to slow or halt the progression of Parkinson's disease …
evidence of disease-modifying effects in Parkinson's disease. The absence of disease-modifying …
evidence of disease-modifying effects in Parkinson's disease. The absence of disease-modifying …
Multitarget therapeutic approaches for Alzheimer's and Parkinson's diseases: an opportunity or an illusion?
MJ Matos - Future Medicinal Chemistry, 2021 - Taylor & Francis
… drug for Alzheimer's disease. (B) Chemical structure of rasagiline, the first US FDA-approved
multitarget drug for Parkinson's disease. With regard to Parkinson's disease, several …
multitarget drug for Parkinson's disease. With regard to Parkinson's disease, several …
Limitations of current Parkinson's disease therapy
… with Parkinson's disease in the early stages of the disease. However, once the “honeymoon”
period has waned, usually after a few years of dopaminergic therapy… in Parkinson's disease. …
period has waned, usually after a few years of dopaminergic therapy… in Parkinson's disease. …
[HTML][HTML] Therapy of Parkinson's disease subtypes
C Marras, KR Chaudhuri, N Titova, TA Mestre - Neurotherapeutics, 2020 - Elsevier
… This review discusses each of the major subtyping systems/methods in terms of its applicability
to therapy in PD, and the opportunities and challenges designing clinical trials to develop …
to therapy in PD, and the opportunities and challenges designing clinical trials to develop …
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