Neuroendocrine tumors: insights into innovative therapeutic options and rational development of targeted therapies

F Barbieri, M Albertelli, F Grillo, A Mohamed… - Drug discovery today, 2014 - Elsevier
… have radically modified our knowledge of neuroendocrine tumor (NET) biology, pathogenesis
and management [1]. NETs derive from neuroendocrine cells of the diffuse endocrine …

The management of neuroendocrine tumours: current and future medical therapy options

KE Öberg - Clinical Oncology, 2012 - Elsevier
… Another therapeutic option for patients is the use of radionuclides to target NETs, although
no randomised phase III trials have reported data. Patients whose tumours continue to grow …

Therapeutic strategies for patients with neuroendocrine neoplasms: current perspectives

R Modica, A Liccardi, R Minotta… - Expert Review of …, 2022 - Taylor & Francis
… Treatment is therefore a challenge for clinicians, although the landscape of the therapeutic
options has considerably expanded in the last decades. Surgery remains the cornerstone of …

Therapeutic options for neuroendocrine tumors: a systematic review and network meta-analysis

RM Kaderli, M Spanjol, A Kollár, L Bütikofer… - JAMA …, 2019 - jamanetwork.com
… patients with neuroendocrine tumors assigned to 22 different therapies. A … therapies for
pancreatic neuroendocrine tumors and 5 therapies for gastrointestinal neuroendocrine tumors

Treatment options for pancreatic neuroendocrine tumors

A Akirov, V Larouche, S Alshehri, SL Asa, S Ezzat - Cancers, 2019 - mdpi.com
… and may serve as an important therapeutic option. … of neuroendocrine tumors have led to
significant changes in our understanding and treatment options for patients with these tumors. …

The safety of available treatments options for neuroendocrine tumors

A Faggiano, F Lo Calzo, G Pizza… - Expert opinion on drug …, 2017 - Taylor & Francis
therapeutic options in NEN has considerably expanded in the last years, thanks to the growing
knowledge of tumor … The current systemic therapies for locally advanced or metastatic G1/…

Emerging treatment options for gastroenteropancreatic neuroendocrine tumors

M Cives, E Pelle', J Strosberg - Journal of Clinical Medicine, 2020 - mdpi.com
Treatment options for neuroendocrine tumors (NETs) and … -emitting peptide receptor
radionuclide therapy (PRRT), and … data on emerging treatments for neuroendocrine neoplasms. …

New treatment options for patients with advanced neuroendocrine tumors

JA Chan, MH Kulke - Current treatment options in oncology, 2011 - Springer
… Well- to moderately differentiated neuroendocrine tumors (NET) are a heterogeneous group
of malignancies for which a range of therapeutic options have been employed. For patients …

Targeted systemic treatment of neuroendocrine tumors: current options and future perspectives

AD Herrera-Martínez, J Hofland, LJ Hofland… - Drugs, 2019 - Springer
… of the currently available treatment options for advanced functional as well as non-… therapeutic
options and clinical trials. We will not discuss systemic chemotherapy or neuroendocrine

[HTML][HTML] Novel therapeutic approaches and mechanisms in neuroendocrine tumors: the role of targeted agents

G Papaxoinis, K Syrigos, MW Saif - Discovery Medicine, 2016 - discoverymedicine.com
… Well-differentiated neuroendocrine tumors (NETs) represent a group of malignancies with
… resistant to SSAs, or rapidly progressing, multiple therapeutic options exist, depending on …