The therapeutic potential of targeting ABC transporters to combat multi-drug resistance
… We also discussed potential therapeutic strategies of targeting ABC transporters to reverse …
ABC transporters and to discuss potential therapeutic strategies of targeting ABC transporters …
ABC transporters and to discuss potential therapeutic strategies of targeting ABC transporters …
ABC transporters: human disease and pharmacotherapeutic potential
… causation and therapeutic potential, underlining … therapies for cystic fibrosis. This review
will explore the growing relevance of ABC transporters to human disease and their potential as …
will explore the growing relevance of ABC transporters to human disease and their potential as …
ABC transporters: unvalidated therapeutic targets in cancer and the CNS
RW Robey, PR Massey… - Anti-Cancer Agents …, 2010 - ingentaconnect.com
… In this review, we will discuss the question of whether ABC transporters mediate drug …
Despite these difficulties, a potential role has emerged for drug transporters as therapeutic targets …
Despite these difficulties, a potential role has emerged for drug transporters as therapeutic targets …
[HTML][HTML] The role of bacterial ATP-binding cassette (ABC) transporters in pathogenesis and virulence: Therapeutic and vaccine potential
AA Akhtar, DPJ Turner - Microbial pathogenesis, 2022 - Elsevier
… We demonstrate how ABC transporters play a vital role in the virulence and pathogenesis of
several … We also show that ABC transporters display considerable potential for therapeutic …
several … We also show that ABC transporters display considerable potential for therapeutic …
Importance of ABC transporters in drug development
M Benadiba, Y Maor - Current pharmaceutical design, 2016 - ingentaconnect.com
… transport numerous essential compounds including lipids and other signaling molecules. ABC
transporters … to carry a multitude of xenobiotics, including therapeutic drugs, and in light of …
transporters … to carry a multitude of xenobiotics, including therapeutic drugs, and in light of …
Exploiting the therapeutic potential of Plasmodium falciparum solute transporters
HM Staines, ET Derbyshire, K Slavic, A Tattersall… - Trends in …, 2010 - cell.com
… an emphasis on their therapeutic potential. It demonstrates the largely untapped potential
of targeting these important pathways (including P-type ATPases, ABC transporters and K + …
of targeting these important pathways (including P-type ATPases, ABC transporters and K + …
ABC transporters in human diseases: future directions and therapeutic perspectives
T Falguières - International Journal of Molecular Sciences, 2022 - mdpi.com
… ATP-binding cassette (ABC) transporters. Mammalian ABC transporters form a protein …
transmembrane proteins, responsible for the active transport of their substrates (ions, drugs, …
transmembrane proteins, responsible for the active transport of their substrates (ions, drugs, …
ABC drug transporters and immunity: novel therapeutic targets in autoimmunity and cancer
R van de Ven, R Oerlemans… - Journal of leukocyte …, 2009 - academic.oup.com
… This review will focus on the expression, regulation, and substrate specificity of ABC transporters
in relation to functional activities of immune effector cells and discusses implications for …
in relation to functional activities of immune effector cells and discusses implications for …
Implication of ABC transporters in non-proliferative diseases
TA Grigoreva, AV Sagaidak, DS Novikova… - European Journal of …, 2022 - Elsevier
… resistant CNS diseases, inhibitors of ABC exporters can show therapeutic potential. In
general, neurological diseases and the role of BBB transporters are demonstrated in a number of …
general, neurological diseases and the role of BBB transporters are demonstrated in a number of …
Investigational ABC transporter inhibitors
… of ABC transporters in cancer progression beyond the efflux of anticancer drugs. We examine
the therapeutic potential of ABC transporter … in development that target ABC transporters. …
the therapeutic potential of ABC transporter … in development that target ABC transporters. …
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