Androgen receptor in human health: a potential therapeutic target
… Abstract: Androgen is a key for the activation of Androgen Receptor (AR) in most of the
disease conditions, however androgen-independent activation of AR is also found in aggressive …
disease conditions, however androgen-independent activation of AR is also found in aggressive …
[HTML][HTML] Androgen/androgen receptor signaling in ovarian cancer: molecular regulation and therapeutic potentials
WM Chung, L Chen, WC Chang, SY Su… - International journal of …, 2021 - mdpi.com
… Androgen receptor (AR) belongs to the nuclear receptor superfamily and can be activated
through binding to its ligand androgens. Studies have reported an association between AR …
through binding to its ligand androgens. Studies have reported an association between AR …
Therapeutic potential of the SARMs: revisiting the androgen receptor for drug discovery
S Segal, R Narayanan, JT Dalton - Expert Opinion on …, 2006 - Taylor & Francis
… The primary hypothesis on which the therapeutic potential section of this review is based is
that SARMs may provide the same beneficial effects as androgens, but without a similar side-…
that SARMs may provide the same beneficial effects as androgens, but without a similar side-…
Novel, potent anti-androgens of therapeutic potential: recent advances and promising developments
TS Vasaitis, VCO Njar - Future medicinal chemistry, 2010 - Taylor & Francis
… androgen receptor (AR) signaling. This review details the current state of anti-androgen therapy,
… Anti-androgen failure has been linked to elevated AR expression, increased expression …
… Anti-androgen failure has been linked to elevated AR expression, increased expression …
Selective androgen receptor modulators in drug discovery: medicinal chemistry and therapeutic potential
R Cadilla, P Turnbull - Current Topics in Medicinal Chemistry, 2006 - ingentaconnect.com
… of the SARM literature up to August 2005 and will put particular emphasis on the therapeutic
potential of this exciting class of molecules. ANDROGEN RECEPTOR PHARMACOLOGY …
potential of this exciting class of molecules. ANDROGEN RECEPTOR PHARMACOLOGY …
Therapeutic potential of leelamine, a novel inhibitor of androgen receptor and castration-resistant prostate cancer
KB Singh, X Ji, SV Singh - Molecular cancer therapeutics, 2018 - AACR
… androgen deprivation therapy remains challenging. CRPC is driven by aberrant activation of
androgen receptor (… Herein, we present experimental evidence for therapeutic vulnerability …
androgen receptor (… Herein, we present experimental evidence for therapeutic vulnerability …
Androgen receptor is a new potential therapeutic target for the treatment of hepatocellular carcinoma
… androgen ablation therapy to treat HCC also leads to inconsistent results. Here we examine
androgen receptor … RNA, we also examined the therapeutic potentials of targeting AR in HCC…
androgen receptor … RNA, we also examined the therapeutic potentials of targeting AR in HCC…
Androgen receptor is a potential therapeutic target for bladder cancer
JT Wu, BM Han, SQ Yu, HP Wang, SJ Xia - Urology, 2010 - Elsevier
… To investigate whether androgen receptor (AR) could serve as a potential molecular target
for the … In this study, our goal was to investigate the therapeutic potential of targeting the AR in …
for the … In this study, our goal was to investigate the therapeutic potential of targeting the AR in …
Androgen receptor as a therapeutic target
W Gao - Advanced drug delivery reviews, 2010 - Elsevier
… Although the structural features required for these interactions are not fully understood,
targeting these functional interfaces may hold therapeutic potential in the treatment of infertility …
targeting these functional interfaces may hold therapeutic potential in the treatment of infertility …
The androgen receptor: a potential target for therapy of prostate cancer
AF Santos, H Huang, DJ Tindall - Steroids, 2004 - Elsevier
… the androgen receptor and its role in prostate cancer. Initially the function of the androgen
receptor will … Next, the clinical diagnosis, epidemiological impact, and treatments of androgen-…
receptor will … Next, the clinical diagnosis, epidemiological impact, and treatments of androgen-…
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