[HTML][HTML] Oleanolic acid and its derivatives: biological activities and therapeutic potential in chronic diseases

TB Ayeleso, MG Matumba, E Mukwevho - Molecules, 2017 - mdpi.com
… reports on the biological effects of oleanolic acid from different plant sources and its …
oleanolic acid and its derivatives are important candidates in the search for alternative therapy

Therapeutic potential of oleanolic acid in liver diseases

Y Wang, K Liu - Naunyn-Schmiedeberg's Archives of Pharmacology, 2024 - Springer
… research suggests that oleanolic acid has a promising therapeutic effect in the … potential
as an effective treatment approach for this condition. However, the precise role of oleanolic acid

Oleanolic acid and ursolic acid: Therapeutic potential in neurodegenerative diseases, neuropsychiatric diseases and other brain disorders

C Chen, Q Ai, A Shi, N Wang, L Wang… - Nutritional …, 2023 - Taylor & Francis
Oleanolic acid (OA) and ursolic acid (UA) are phytochemicals belong to the group of
pentacyclic triterpenoids, and widely distributed in plants. Recently, the therapeutic potential of OA …

Beneficial actions of oleanolic acid in an experimental model of multiple sclerosis: a potential therapeutic role

R Martín, J Carvalho-Tavares, M Hernández… - Biochemical …, 2010 - Elsevier
Oleanolic acid (OA), a natural pentacyclic triterpene widely … numerous biological properties
with therapeutic potential [7], [8]… derivatives based on oleanolic acid has been synthesized, in …

[HTML][HTML] Prophylactic and therapeutic roles of oleanolic acid and its derivatives in several diseases

A Sen - World Journal of Clinical Cases, 2020 - ncbi.nlm.nih.gov
… Core tip: Oleanolic acid (OA) is plentiful in many fruits and vegetables. Studies have shown
… have crucial prophylactic and therapeutic potential for diseases including ulcerative colitis, …

Oleanolic acid derivatives for pharmaceutical use: A patent review

C Lin, X Wen, H Sun - Expert opinion on therapeutic patents, 2016 - Taylor & Francis
… to undoubtedly confirm the clinical potential of oleanolic acid and its derivatives. Based on
… Together, there is a huge potential for drug-repositioning of oleanolic acid, particularly in the …

Oleanolic acid and its synthetic derivatives for the prevention and therapy of cancer: preclinical and clinical evidence

MK Shanmugam, X Dai, AP Kumar, BKH Tan, G Sethi… - Cancer letters, 2014 - Elsevier
… Major inflammation-associated signaling pathways inhibited by synthetic derivatives of
oleanolic acid. These pathways include NF-κB, STAT3, TRAIL signal transduction pathways and …

Therapeutic potentials of triterpenes in diabetes and its associated complications

S Putta, N Sastry Yarla, E Kumar Kilari… - Current topics in …, 2016 - ingentaconnect.com
… food and medicinal herbs contains Oleanolic acid, which is endowed with a wide range of
… of triterpenes like ursolic acid, oleanolic acid, betulinic acid. These triterpenes bind at the …

[HTML][HTML] Oleanolic acid: extraction, characterization and biological activity

JM Castellano, S Ramos-Romero, JS Perona - Nutrients, 2022 - mdpi.com
Oleanolic acid is endowed with a wide range of biological activities with therapeutic potential
… There is evidence suggesting that oleanolic acid might be effective against dyslipidemia, …

[HTML][HTML] Therapeutic potential of ursonic acid: comparison with ursolic acid

J Son, SY Lee - Biomolecules, 2020 - mdpi.com
… not well-known, in this work, we attempt to introduce the therapeutic potential of UNA with
a comparison to ursolic acid (ULA), a well-known secondary metabolite, for beneficial effects. …