Diagnostic and therapeutic potential of microRNAs in acute kidney injury

T Brandenburger, JM Lorenzen - Frontiers in pharmacology, 2020 - frontiersin.org
… an episode of acute kidney injury (AKI), which is characterized by a rapid decrease in …
in the context of AKI while critically evaluating their diagnostic and therapeutic potential. …

The role of mitochondria in acute kidney injury and chronic kidney disease and its therapeutic potential

X Zhang, E Agborbesong, X Li - International journal of molecular …, 2021 - mdpi.com
… Recent studies have been focusing on how mitochondrial dysfunction contributes to the
pathogenesis of different forms of kidney diseases, including acute kidney injury (AKI) and …

Ferroptosis and acute kidney injury (AKI): molecular mechanisms and therapeutic potentials

Q Feng, X Yu, Y Qiao, S Pan, R Wang… - Frontiers in …, 2022 - frontiersin.org
… However, the exact mechanism of ferroptosis participating in the initiation and progression of
AKI has … in AKI development. We further conclude its potential therapeutic strategies in AKI. …

Acute kidney injury overview: from basic findings to new prevention and therapy strategies

SR Gonsalez, AL Cortês, RC da Silva, J Lowe… - … & therapeutics, 2019 - Elsevier
Acute kidney injury (AKI) is defined as a decrease in kidney function within hours, which
encompasses both injury and impairment of renalAcute kidney injury (AKI) is characterized by …

Mechanistic aspects and therapeutic potential of quercetin against COVID-19-associated acute kidney injury

LRL Diniz, MTS Souza, ABS Duarte, DP Sousa - Molecules, 2020 - mdpi.com
Acute kidney injury (AKI) is a common renal disorder characterized by a … on AKI induced
by very diverse nephrotoxic stimuli. Its therapeutic potential for COVID-19-related renal injury

P53 in kidney injury and repair: mechanism and therapeutic potentials

C Tang, Z Ma, J Zhu, Z Liu, Y Liu, Y Liu, J Cai… - … & therapeutics, 2019 - Elsevier
Acute kidney injury (AKI) is a major kidney disease with poor clinical outcome. Besides
its acute consequence of high mortality, AKI … and progression of chronic kidney diseases (CKD). …

[HTML][HTML] Mechanisms and therapeutic targets of ischemic acute kidney injury

SJ Han, HT Lee - Kidney research and clinical practice, 2019 - ncbi.nlm.nih.gov
Acute kidney injury (AKI) due to renal ischemia reperfusion (IR) is a major clinical problem
without effective therapy and … Although the pathophysiology of ischemic AKI is not completely …

[HTML][HTML] Impact of acute kidney injury on distant organ function: recent findings and potential therapeutic targets

K Doi, H Rabb - Kidney international, 2016 - Elsevier
… Mechanical supports including renal replacement therapy (RRT) do not sufficiently
improve the outcomes of patients with acute kidney injury (AKI) treated in intensive care units, …

Therapeutic potential of stem cells from human exfoliated deciduous teeth in models of acute kidney injury

Y Hattori, H Kim, N Tsuboi, A Yamamoto, S Akiyama… - PLoS …, 2015 - journals.plos.org
… a therapeutic effect on AKI induced by … Acute kidney injury (AKI) is a critical condition
associated with high mortality rates of 30 to 50%. AKI has various pathoetiologies; ischemic kidney

Short-term preconditioning enhances the therapeutic potential of adipose-derived stromal/stem cell-conditioned medium in cisplatin-induced acute kidney injury

JM Overath, S Gauer, N Obermüller, R Schubert… - Experimental cell …, 2016 - Elsevier
… The development of new strategies to preserve renal function after acute kidney injury (AKI) …
the outcome of AKI. Nevertheless, strategies to optimise the regenerative potential of both …