Emerging role of mitophagy in the heart: therapeutic potentials to modulate mitophagy in cardiac diseases

Y Luan, Y Luan, Q Feng, X Chen… - … Medicine and Cellular …, 2021 - Wiley Online Library
… disease, diabetic cardiomyopathy, cardiac hypertrophy, heart failure, and arrhythmia, and …
mitophagy. We also discuss recently reported approaches targeting mitophagy in the therapy

Autophagy and mitophagy in the myocardium: therapeutic potential and concerns

RE Jimenez, DA Kubli… - British journal of …, 2014 - Wiley Online Library
… These studies did not assess whether autophagy and mitochondrial clearance are enhanced
in these hearts, so it is unclear if excessive mitophagy contributes to the cardiac phenotype …

Mitochondrial function in the heart: the insight into mechanisms and therapeutic potentials

BY Nguyen, A Ruiz‐Velasco, T Bui… - British journal of …, 2019 - Wiley Online Library
… This has highlighted the therapeutic potential of targeting mitochondria to prevent or treat …
roles of mitophagy in the heart in response to stress. For instance, hearts subjected to ex …

[HTML][HTML] Autophagy and mitophagy as potential therapeutic targets in diabetic heart condition: Harnessing the power of nanotheranostics

S Nag, O Mitra, B Maturi, SP Kaur, A Saini… - Asian Journal of …, 2024 - Elsevier
… of nanotechnology to target autophagy and mitophagy in DHC, offering a promising … therapies.
This article aims to explore the potential connections between autophagy, mitophagy and …

Mitophagy receptors and mediators: therapeutic targets in the management of cardiovascular ageing

A Ajoolabady, H Aslkhodapasandhokmabad… - Ageing Research …, 2020 - Elsevier
… defect in aged hearts. These investigators revealed that SS-31 treatment rescued aged hearts
from … for regulation of mitophagy and their therapeutic potentials in cardiovascular ageing. …

Mitochondrial fusion, fission, and mitophagy in cardiac diseases: challenges and therapeutic opportunities

DL Scheffer, AA Garcia, L Lee… - Antioxidants & Redox …, 2022 - liebertpub.com
… -Fis1 protein/protein interaction, seems to have a therapeutic potential in preventing
ischemia-induced cardiac injury and the subsequent establishment of heart failure (Fig. 6). Similar …

Emerging role of mitophagy in cardiovascular physiology and pathology

PE Morales, C Arias-Durán, Y Ávalos-Guajardo… - Molecular aspects of …, 2020 - Elsevier
mitophagy in cardiovascular physiology and pathology, focusing on the therapeutic potential
of mitophagy … we discuss associations between mitophagy and various heart conditions. To …

Mending a broken heart: the role of mitophagy in cardioprotection

AG Moyzis, J Sadoshima… - … of Physiology-Heart …, 2015 - journals.physiology.org
mitophagy in response to stress and aging. We also discuss the therapeutic potential of targeting
mitophagy … We also highlight the therapeutic potential of targeting mitophagy, as well as …

Autophagy and cardiac diseases: Therapeutic potential of natural products

X Wu, Z Liu, XY Yu, S Xu, J Luo - Medicinal Research Reviews, 2021 - Wiley Online Library
… A shift from isoform AMPKα2 to AMPKα1 was observed in the hearts of heart failure patients,
mitophagy to prevent heart failure in mice, 68 suggesting its involvement of mitophagy in the …

Mitophagy in cardiovascular diseases

G Morciano, S Patergnani, M Bonora, G Pedriali… - Journal of clinical …, 2020 - mdpi.com
… for the development of potential therapies. Here, we summarize the current knowledge on
mitophagy (and autophagy) mechanisms in the context of heart disease with an important …