Benchmark for time in therapeutic range in venous thromboembolism: a systematic review and meta-analysis

PMG Erkens, H ten Cate, HR Büller, MH Prins - 2012 - journals.plos.org
… A target INR range of 2.0 to 3.0 is recommended for the treatment of VTE [3]. The … therapeutic
effectiveness of VKA over time is to measure the percentage of time in the therapeutic range

Frequency of adverse events in patients with poor anticoagulation: a meta-analysis

N Oake, DA Fergusson, AJ Forster, C Van Walraven - Cmaj, 2007 - Can Med Assoc
… 3 INR ranges: below, within and above the therapeutic range. … INRs exceeded the therapeutic
range and the proportion of … that occurred above therapeutic range and overall mean …

Meta-analysis of safety and efficacy of direct oral anticoagulants versus warfarin according to time in therapeutic range in atrial fibrillation

JJ Lee, ACT Ha, P Dorian, M Verma… - The American Journal of …, 2021 - Elsevier
… time in therapeutic range (TTR), we conducted a systematic review and meta-analysis of
published … Based on reported center-based TTR (cTTR) ranges, degrees of INR control were …

Anticoagulation intensity and outcomes among patients prescribed oral anticoagulant therapy: a systematic review and meta-analysis

N Oake, A Jennings, AJ Forster, D Fergusson… - Cmaj, 2008 - Can Med Assoc
… higher than this therapeutic range appear safe and … 3 ranges of international normalized
ratios (< 2, 2–3 and > 3). We included studies irrespective of therapeutic indication, target range

Metaanalysis of time in therapeutic range in continuous‐flow left ventricular assist device patients receiving warfarin

BK Martinez, B Yik, R Tran, S Ilham… - Artificial …, 2018 - Wiley Online Library
meta-analysis demonstrates that CF-LVAD patients are outside of their therapeutic INR range
… For example, a meta-analysis of 78 atrial fibrillation studies found a mean TTR of 61% (95…

Meta-analysis to assess the quality of warfarin control in atrial fibrillation patients in the United States

WL Baker, DA Cios, SD Sander, CI Coleman - Journal of Managed Care …, 2009 - jmcp.org
… , with about 66% of the time in therapeutic range for anticoagulation therapy in both randomized
controlled trials and anticoagulation clinics as compared with 57% for community-based …

Meta-analysis of research on the effect of clinical pharmacokinetics services on therapeutic drug monitoring

LD Ried, DA McKenna, JR Horn - American Journal of Health …, 1989 - academic.oup.com
… patients were more likely to have therapeutic peak (ES = 0.51… concentrations, to be within
therapeutic range (ES = 0.91, 95… concentrations within the therapeutic range and reducing the …

Quality of vitamin K antagonist control and outcomes in atrial fibrillation patients: a meta-analysis and meta-regression

ES Mearns, CM White, CG Kohn, J Hawthorne… - Thrombosis journal, 2014 - Springer
… We evaluated time spent in therapeutic range (TTR), proportion of international normalized
… of events that occurred outside the therapeutic range for 59% of thromboembolic events (95…

… with thromboembolic complications: meta-analysis of 2 prospective trials to assess the value of parenteral treatment with lepirudin and its therapeutic aPTT range

A Greinacher, P Eichler, N Lubenow… - Blood, The Journal …, 2000 - ashpublications.org
… This meta-analysis focuses on 2 prospective studies in … HIT and the start of lepirudin therapy
(combined event rate per patient … From the start of lepirudin therapy to the end of follow-up, …

A systematic review and metaanalysis on the therapeutic equivalence of statins

TC Weng, YHK Yang, SJ Lin… - Journal of clinical …, 2010 - Wiley Online Library
… doses of statins, we first determined specific ranges of LDL-C reduction (ie reduce LDL 30–…
in previous RCTs to achieve similar ranges in LDL reduction, meta-analyses were performed …