[HTML][HTML] Drug repurposing: A novel strategy to target cancer stem cells and therapeutic resistance
D Ajmeera, R Ajumeera - Genes & Diseases, 2024 - Elsevier
… non-cancerous drugs with anticancer activity… drug repurposing and the combination of
micronutrients that can target both cancers and cancer stem cells may result in a better therapeutic …
micronutrients that can target both cancers and cancer stem cells may result in a better therapeutic …
Overcoming therapy resistance in colon cancer by drug repurposing
… current data supporting drug repurposing as a … drug repurposing as a feasible option for
patients with CRC with a focus on the evidence and mechanism of action promising repurposed …
patients with CRC with a focus on the evidence and mechanism of action promising repurposed …
Overcoming cancer therapeutic bottleneck by drug repurposing
… non-oncology drugs for clinical cancer management and classify these candidates into their
… - or drug combination therapy. We also summarize approaches used for drug repurposing …
… - or drug combination therapy. We also summarize approaches used for drug repurposing …
Drug repurposing to overcome resistance to various therapies for colorectal cancer
W Fong, KKW To - Cellular and molecular life sciences, 2019 - Springer
… While novel drug development is unfavorable in terms of time frame and costs, drug
repurposing is one of the promising strategies to combat resistance. This approach refers to the …
repurposing is one of the promising strategies to combat resistance. This approach refers to the …
[HTML][HTML] Drug repurposing for next-generation combination therapies against multidrug-resistant bacteria
… discovery and the development of bacterial resistance. We summarize drug-drug interactions
and uncover the art of repurposing non-antibiotic drugs as potential antibiotic adjuvants, …
and uncover the art of repurposing non-antibiotic drugs as potential antibiotic adjuvants, …
Drug repurposing to overcome microbial resistance
J Jampilek - Drug Discovery Today, 2022 - Elsevier
… vitro antimicrobial activity to support existing anti-infective therapeutics is provided, including
several critical remarks on this strategy of repurposing non-antibiotics to antibacterial drugs. …
several critical remarks on this strategy of repurposing non-antibiotics to antibacterial drugs. …
Overcoming drug resistance in advanced prostate cancer by drug repurposing
… , affecting stromal, endothelial, and immune cells, as well as promoting epithelial-to-mesenchymal
transition, which is believed to be a contributor to therapy resistance in PCa [20,21]. …
transition, which is believed to be a contributor to therapy resistance in PCa [20,21]. …
Drug repurposing—an emerging strategy in cancer therapeutics
KS Turabi, A Deshmukh, S Paul, D Swami… - Naunyn-Schmiedeberg's …, 2022 - Springer
… may make them suitable to be repurposed as cancer therapeutics (Fig. 1). This review article
also includes the clinical trial status of repurposed drugs, which are currently being focused …
also includes the clinical trial status of repurposed drugs, which are currently being focused …
Repurposing old drugs to fight multidrug resistant cancers
… resistance represents a major challenge for cancer treatment. In the search for new
chemotherapeutics to treat malignant diseases, drug repurposing … for cancer therapeutics. These …
chemotherapeutics to treat malignant diseases, drug repurposing … for cancer therapeutics. These …
[HTML][HTML] Improving therapy of severe infections through drug repurposing of synergistic combinations
YS Cheng, PR Williamson, W Zheng - Current opinion in pharmacology, 2019 - Elsevier
… in 2014, our group performed a drug repurposing screen which identified a set of 53
Ebola-entry inhibitors [45]. However, the human plasma drug concentrations of most of these …
Ebola-entry inhibitors [45]. However, the human plasma drug concentrations of most of these …
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