Microenvironmental regulation of therapeutic response in cancer
… the TME regulates therapeutic response, a field … therapeutic outcome in either a positive
or a negative manner. Harnessing this expanding knowledge to improve therapeutic response …
or a negative manner. Harnessing this expanding knowledge to improve therapeutic response …
Modulating the microbiome to improve therapeutic response in cancer
JL McQuade, CR Daniel, BA Helmink… - The Lancet …, 2019 - thelancet.com
… therapeutic responses to cancer treatment. Importantly, microbiota can be modified via several
different strategies, affording new angles in cancer … in cancer and therapeutic response, …
different strategies, affording new angles in cancer … in cancer and therapeutic response, …
Tumor microenvironment and therapeutic response
T Wu, Y Dai - Cancer letters, 2017 - Elsevier
… While the role of the TME during tumorigenesis has recently been reviewed in detail
elsewhere [1], [2], in this review, we focus on how the TME regulates therapeutic response and …
elsewhere [1], [2], in this review, we focus on how the TME regulates therapeutic response and …
Influence of tumour micro-environment heterogeneity on therapeutic response
MR Junttila, FJ De Sauvage - Nature, 2013 - nature.com
… influence therapeutic response … cancer are often treated through multiple lines of therapy,
serial biopsies from different sites may be required to predict response and implement therapy. …
serial biopsies from different sites may be required to predict response and implement therapy. …
Why therapeutic response may not prolong the life of a cancer patient: selection for oncogenic resistance
MV Blagosklonny - Cell cycle, 2005 - Taylor & Francis
… Now we can reexamine the question of whether or not therapeutic response should not
increase overall survival? As shown in Figure 2, therapy kills proliferating cells, leading to …
increase overall survival? As shown in Figure 2, therapy kills proliferating cells, leading to …
[HTML][HTML] MicroRNAs in cancer therapeutic response: Friend and foe
J Xue, J Niu, J Wu, ZH Wu - World journal of clinical oncology, 2014 - ncbi.nlm.nih.gov
… function in cancer initiation, metastasis and therapeutic response, focusing on breast cancer.
The … as well as therapeutic approaches are further discussed in the context of different …
The … as well as therapeutic approaches are further discussed in the context of different …
Molecular pathways: involvement of immune pathways in the therapeutic response and outcome in breast cancer
F Andre, MV Dieci, P Dubsky, C Sotiriou… - Clinical cancer …, 2013 - AACR
… treatment efficacy and outcome in patients with breast cancers. As examples, intratumoral
infiltration by lymphocytes and interferon-response in primary tumor predicted the efficacy of …
infiltration by lymphocytes and interferon-response in primary tumor predicted the efficacy of …
Consensus recommendations for the use of 18F-FDG PET as an indicator of therapeutic response in patients in National Cancer Institute Trials
LK Shankar, JM Hoffman, S Bacharach… - Journal of Nuclear …, 2006 - Soc Nuclear Med
… therapeutic clinical trials have proposed using a measure of metabolic change to assess
therapeutic response … as a biomarker for predicting therapeutic response, there are no widely …
therapeutic response … as a biomarker for predicting therapeutic response, there are no widely …
The role of chromosomal instability in cancer and therapeutic responses
N Vargas-Rondón, VE Villegas, M Rondón-Lagos - Cancers, 2017 - mdpi.com
… and others associating it with therapeutic resistance. … , but also in therapeutic responses.
This review focuses on recent … a primary focus on cancer outcomes and therapeutic responses. …
This review focuses on recent … a primary focus on cancer outcomes and therapeutic responses. …
Gene expression profiling for the prediction of therapeutic response to docetaxel in patients with breast cancer
JC Chang, EC Wooten, A Tsimelzon, SG Hilsenbeck… - The Lancet, 2003 - thelancet.com
… cancer substantially decreases the risk of death. Patients often have de novo resistance or
incomplete response to … of the primary breast cancer can predict the response to docetaxel. …
incomplete response to … of the primary breast cancer can predict the response to docetaxel. …
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