Tumor microenvironment and therapeutic response
T Wu, Y Dai - Cancer letters, 2017 - Elsevier
… While the role of the TME during tumorigenesis has recently been reviewed in detail
elsewhere [1], [2], in this review, we focus on how the TME regulates therapeutic response and …
elsewhere [1], [2], in this review, we focus on how the TME regulates therapeutic response and …
Microenvironmental regulation of therapeutic response in cancer
… on how the TME regulates therapeutic response, a field that has … the tumor microenvironment
(TME) and TME-targeted therapies. … response and are putative candidates for therapeutic …
(TME) and TME-targeted therapies. … response and are putative candidates for therapeutic …
Influence of tumour micro-environment heterogeneity on therapeutic response
MR Junttila, FJ De Sauvage - Nature, 2013 - nature.com
… influence therapeutic response and shape resistance. … anti-VEGF therapy by a pro-inflammatory
micro-environment that … abundance may impede therapeutic responses. After radiation …
micro-environment that … abundance may impede therapeutic responses. After radiation …
Tumor microenvironment and differential responses to therapy
E Hirata, E Sahai - Cold Spring Harbor …, 2017 - perspectivesinmedicine.cshlp.org
… tumor microenvironment can modulate the response to chemo- and radiotherapy. We further
describe how therapeutic … function, of the tumor microenvironment, thereby further altering …
describe how therapeutic … function, of the tumor microenvironment, thereby further altering …
Monitoring immune responses in the tumor microenvironment
JA Wargo, SM Reddy, A Reuben, P Sharma - Current opinion in …, 2016 - Elsevier
… realize the potential to obtain a dynamic and comprehensive understanding of tumor-microenvironment
interactions, as well as their relationship to therapeutic response and resistance. …
interactions, as well as their relationship to therapeutic response and resistance. …
Autophagy: shaping the tumor microenvironment and therapeutic response
H Maes, N Rubio, AD Garg, P Agostinis - Trends in molecular medicine, 2013 - cell.com
… of established tumors. Likewise, the stimulation of autophagy in response to therapeutics can
… From a therapeutic perspective, understanding whether, when, and how autophagy can be …
… From a therapeutic perspective, understanding whether, when, and how autophagy can be …
Impact of tumor microenvironment composition on therapeutic responses and clinical outcomes in cancer
F Anari, C Ramamurthy, M Zibelman - Future Oncology, 2018 - Taylor & Francis
The tumor microenvironment (TME) plays an important role in cancer growth and progression.
Paradoxically, the TME is capable of acting as both a potential barrier and facilitator of …
Paradoxically, the TME is capable of acting as both a potential barrier and facilitator of …
Patient-derived models reveal impact of the tumor microenvironment on therapeutic response
AA Shafi, MJ Schiewer, R de Leeuw, E Dylgjeri… - European urology …, 2018 - Elsevier
… effective therapies is the lack of preclinical models that adequately recapitulate the
heterogeneity of PCa, significantly hindering the ability to accurately predict therapeutic response. …
heterogeneity of PCa, significantly hindering the ability to accurately predict therapeutic response. …
Myeloid cell signatures in tumor microenvironment predicts therapeutic response in cancer
… and thus, enhance tumor growth. Next, we have discussed the contribution of key myeloid
populations in the therapeutic responses. Myeloid cell signatures in therapeutic response …
populations in the therapeutic responses. Myeloid cell signatures in therapeutic response …
Tumor microenvironment as a therapeutic target in cancer
Y Xiao, D Yu - Pharmacology & therapeutics, 2021 - Elsevier
… play critical roles in tumor progression and therapeutic responses, attention has been … tumor
microenvironment (TME). The TME comprises all the non-cancerous host cells in the tumor, …
microenvironment (TME). The TME comprises all the non-cancerous host cells in the tumor, …
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