The NLRP3 inflammasome and COVID-19: Activation, pathogenesis and therapeutic strategies
N Zhao, B Di, L Xu - Cytokine & growth factor reviews, 2021 - Elsevier
… NLRP3 inflammasome activation pathway. Second, we review the cellular/molecular
mechanisms of NLRP3 inflammasome … the involvement of the NLRP3 inflammasome in the …
mechanisms of NLRP3 inflammasome … the involvement of the NLRP3 inflammasome in the …
[HTML][HTML] Targeting the NLRP3 inflammasome as a new therapeutic option for overcoming cancer
… In this review, we will discuss the NLRP3 inflammasome as a … on current strategies for targeting
the NLRP3 inflammasome, … and that targeting NLRP3 is a promising therapeutic strategy. …
the NLRP3 inflammasome, … and that targeting NLRP3 is a promising therapeutic strategy. …
Targeting the NLRP3 inflammasome in inflammatory diseases
MSJ Mangan, EJ Olhava, WR Roush… - Nature reviews Drug …, 2018 - nature.com
… Pharmacological inhibition of NLRP3 activation results in potent therapeutic effects in a
wide variety of rodent models of inflammatory diseases, effects that are mirrored by genetic …
wide variety of rodent models of inflammatory diseases, effects that are mirrored by genetic …
[HTML][HTML] Phytochemicals as novel therapeutic strategies for NLRP3 inflammasome-related neurological, metabolic, and inflammatory diseases
… about the pathophysiological role of NLRP3 inflammasome pathways in such … NLRP3
inflammasome by phytochemicals could represent a promising molecular target for the therapeutic …
inflammasome by phytochemicals could represent a promising molecular target for the therapeutic …
[HTML][HTML] Chronic kidney disease and NLRP3 inflammasome: Pathogenesis, development and targeted therapeutic strategies
G Huang, Y Zhang, Y Zhang, Y Ma - Biochemistry and biophysics reports, 2023 - Elsevier
… of CKD, but the mechanism behind inflammasome activation in CKD remains obscure.In this
… the NLRP3 inflammasome in CKD and new strategies targeting the NLRP3 inflammasome. …
… the NLRP3 inflammasome in CKD and new strategies targeting the NLRP3 inflammasome. …
The NLRP3 inflammasome: Mechanism of action, role in disease and therapies
L Wang, AV Hauenstein - Molecular aspects of medicine, 2020 - Elsevier
… mechanisms of NLRP3 inflammasome activation, how dysregulation of NLRP3 inflammasome
activation causes disease, and potential therapeutics that inhibit NLRP3 inflammasome …
activation causes disease, and potential therapeutics that inhibit NLRP3 inflammasome …
[HTML][HTML] Natural products as a novel therapeutic strategy for NLRP3 inflammasome-mediated gout
JH Lee, HS Kim, JH Lee, G Yang, HJ Kim - Frontiers in Pharmacology, 2022 - frontiersin.org
… through the regulation of NLRP3 inflammasome assembly. In this report, we present an
overview of studies regarding NLRP3 inflammasome-based therapeutic development of natural …
overview of studies regarding NLRP3 inflammasome-based therapeutic development of natural …
Targeting the NLRP3 inflammasome in diabetic retinopathy: From pathogenesis to therapeutic strategies
Y Yang, G Jiang, R Huang, Y Liu, X Chang… - Biochemical …, 2023 - Elsevier
… NLRP3 inflammasome activation. Furthermore, we discuss the implications of the NLRP3
inflammasome … on targeting the NLRP3 inflammasome in DR therapeutics with the expectation …
inflammasome … on targeting the NLRP3 inflammasome in DR therapeutics with the expectation …
The strategies of targeting the NLRP3 inflammasome to treat inflammatory diseases
… Therapies targeting the NLRP3 inflammasome have attractive potential. However, several
… will be elicited in vivo if the therapeutic strategies are designed by targeting the upstream or …
… will be elicited in vivo if the therapeutic strategies are designed by targeting the upstream or …
The involvement of NLRP3 inflammasome in the treatment of Alzheimer's disease
YS Feng, ZX Tan, LY Wu, F Dong, F Zhang - Ageing research reviews, 2020 - Elsevier
… of the molecular mechanisms associated with the onset and progression of AD is critical to
provide a theoretical basis for the establishment of novel preventive and therapeutic strategies…
provide a theoretical basis for the establishment of novel preventive and therapeutic strategies…
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