Pathophysiological mechanisms of renal fibrosis: a review of animal models and therapeutic strategies

A Nogueira, MJ Pires, PA Oliveira - In vivo, 2017 - iv.iiarjournals.org
renal fibrosis. Therefore it is essential to improve our knowledge of the cellular and molecular
… of the progress of renal fibrosis in order to achieve a reversion/elimination of renal fibrosis. …

Oxidative stress and renal fibrosis: recent insights for the development of novel therapeutic strategies

W Lv, GW Booz, F Fan, Y Wang, RJ Roman - Frontiers in physiology, 2018 - frontiersin.org
… , which could form the basis for new therapeutic approaches. This review focuses on the …
to renal fibrosis and provides an update on the development of novel anti-oxidant therapies

Therapeutic strategies to halt renal fibrosis

L Yu, NA Noble, WA Border - Current opinion in pharmacology, 2002 - Elsevier
… growth factor β (TGF-β) have therapeutic promise. Finally, we make an argument for
therapeutic strategies that, with refinement, may truly halt the progression of renal fibrosis. …

[HTML][HTML] Renal fibrosis: new insights into the pathogenesis and therapeutics

Y Liu - Kidney international, 2006 - Elsevier
… Many therapeutic interventions appear effective in animal models; however, … to renal
fibrosis, and discusses the challenges and opportunities in developing therapeutic strategies. …

New therapeutic targets in chronic kidney disease progression and renal fibrosis

S Rayego-Mateos, JM Valdivielso - Expert Opinion on Therapeutic …, 2020 - Taylor & Francis
renal and infiltrating cell types [Citation81]. Among many cells involved in the extraglomerular
renal fibrotic … lead to the development of effective therapeutic strategies to restore, or at …

[图书][B] Renal Fibrosis: Mechanisms and Therapies

BC Liu, HY Lan, LL Lv - 2019 - Springer
renal fibrosis. The possible mechanisms, biomarkers, and strategies for prevention and
treatment of renal fibrosis … a comprehensive understanding of the renal fibrosis. Finally, we would …

Potential approaches to reverse or repair renal fibrosis

D Tampe, M Zeisberg - Nature Reviews Nephrology, 2014 - nature.com
Therapeutic strategies directed at the tubular epithelium can inhibit tubular epithelial cell-derived
chemokines, inhibit or reverse EMT to retain tubular homeostasis, prevent cell death or …

Oxidative stress and renal fibrosis: mechanisms and therapies

H Su, C Wan, A Song, Y Qiu, W Xiong… - Renal Fibrosis …, 2019 - Springer
renal fibrosis as we elucidated above, and thus, targeting OS seems to be a promising strategy
in renal fibrosis … CKD progression by reducing renal fibrosis in preclinical or clinical trials. …

Kidney allograft fibrosis: Diagnostic and therapeutic strategies

T Saritas, R Kramann - Transplantation, 2021 - journals.lww.com
… in the progress of renal fibrosis, diagnosis and therapy of allograft fibrosis. This review …
producing cells and therapeutic targets in renal fibrosis with a particular focus on renal allografts. …

[HTML][HTML] Defining therapeutic targets for renal fibrosis: Exploiting the biology of pathogenesis

H Yan, J Xu, Z Xu, B Yang, P Luo, Q He - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Renal fibrosis is a serious problem that threatens human life … a lack of effective therapeutic
strategies. As a consequence, … of renal fibrosis and looking for effective intervention strategies, …