Targeted therapies and biomarkers in small cell lung cancer
… therapeutic strategies. In this opinion article, we will discuss recent developments in the
treatment of SCLC, focused on current understanding of the signaling pathways, the role of …
treatment of SCLC, focused on current understanding of the signaling pathways, the role of …
[HTML][HTML] Role of epidermal growth factor receptor in lung cancer and targeted therapies
TC Liu, X Jin, Y Wang, K Wang - American Journal of Cancer …, 2017 - ncbi.nlm.nih.gov
… (NSCLC) and Small cell lung cancers (SCLC), have responded effectively to chemo-, …
adjuvant-therapies. Tumor removal through surgery also appeared as a good therapeutic strategy. …
adjuvant-therapies. Tumor removal through surgery also appeared as a good therapeutic strategy. …
A combinatorial strategy for treating KRAS-mutant lung cancer
E Manchado, S Weissmueller, JP Morris, CC Chen… - Nature, 2016 - nature.com
… therapeutic strategies combining trametinib with an FGFR1 inhibitor could be effective in
treating some KRAS-mutant lung cancers … against FGFR1-amplified lung cancer (Extended Data …
treating some KRAS-mutant lung cancers … against FGFR1-amplified lung cancer (Extended Data …
Genetic and immunologic therapies for lung cancer
SG Swisher, JA Roth, DP Carbone - Seminars in oncology, 2002 - Elsevier
… for novel therapeutic strategies for lung cancer is clear. Several such strategies are under
development, and we will review some aspects of two such classes here: gene therapy and …
development, and we will review some aspects of two such classes here: gene therapy and …
Therapeutic advances in non‐small cell lung cancer: Focus on clinical development of targeted therapy and immunotherapy
Y Cheng, T Zhang, Q Xu - MedComm, 2021 - Wiley Online Library
… therapeutic strategies of … lung cancer in China is estimated and may increase by approximately
40% from 2015 to 2030. Thus, the public health and therapeutic strategies for lung cancer…
40% from 2015 to 2030. Thus, the public health and therapeutic strategies for lung cancer…
Emerging insights of tumor heterogeneity and drug resistance mechanisms in lung cancer targeted therapy
ZF Lim, PC Ma - Journal of hematology & oncology, 2019 - Springer
… remarkably to the same therapy [15, 16]… therapy has transformed the face of lung cancer
treatment. Despite great promises brought about by the new paradigm of cancer targeted therapy…
treatment. Despite great promises brought about by the new paradigm of cancer targeted therapy…
A synthetic lethal interaction between K-Ras oncogenes and Cdk4 unveils a therapeutic strategy for non-small cell lung carcinoma
M Puyol, A Martín, P Dubus, F Mulero, P Pizcueta… - Cancer cell, 2010 - cell.com
We have unveiled a synthetic lethal interaction between K-Ras oncogenes and Cdk4 in a
mouse tumor model that closely recapitulates human non-small cell lung carcinoma (NSCLC). …
mouse tumor model that closely recapitulates human non-small cell lung carcinoma (NSCLC). …
Tumor–stromal interactions in lung cancer: novel candidate targets for therapeutic intervention
N El-Nikhely, L Larzabal, W Seeger… - Expert opinion on …, 2012 - Taylor & Francis
… the therapeutic strategies … therapeutic strategies currently being applied in preclinical or
clinical trials and discusses future directions in the context of novel diagnostic and therapeutic …
clinical trials and discusses future directions in the context of novel diagnostic and therapeutic …
Progress in the therapy of small cell lung cancer
M Simon, A Argiris, JR Murren - Critical reviews in oncology/hematology, 2004 - Elsevier
… Antibody and biologic therapy Better understanding of the biology of SCLC has led to the
evaluation of novel therapeutic strategies. In an effort to enhance immune surveillance, …
evaluation of novel therapeutic strategies. In an effort to enhance immune surveillance, …
Adding checkpoint inhibitors to tyrosine kinase inhibitors targeting EGFR/ALK in non-small cell lung cancer: a new therapeutic strategy
S Tabchi, HR Kourie, J Kattan - Investigational new drugs, 2016 - Springer
After the massive approval of checkpoint inhibitors in the treatment of numerous malignancies
and settings, checkpoint inhibitors-based combination therapies are emerging as a new …
and settings, checkpoint inhibitors-based combination therapies are emerging as a new …