… in direct targeting of RBPs or in specific selection of interacting mRNAs. Alternatively, we
can use downstream effectors of RBPs as therapeutic target. For example, MYC is a target of …

Chronic inflammation is a critical modulator of carcinogenesis through secretion of inflammatory
cytokines, which leads to the formation of an inflammatory microenvironment. In this …

Interleukin-6 (IL-6) is an inflammatory cytokine with a well-documented role in cancer. The
cytokine binds to a membrane-bound IL-6 receptor (IL-6R) and this complex associates with …

… that raising HDL may represent an additional therapeutic target for prevention of CVD. …
Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. N …

Hypercholesterolemia is one of the main risk factors for the development of atherosclerosis.
Among the various lipoprotein classes, however, high density lipoproteins (HDL) are …

AMPK is a serine/threonine protein kinase that has the function of maintaining the balance
between ATP production and consumption in most eukaryotic cells. It plays a relevant role in …

Intestinal adhesions are bands of fibrous tissue that connect the loops of the intestine to each
other, to other abdominal organs or to the abdominal wall 1 , 2 , 3 . Fibrous tissue formation …

Rationale: It has been proposed that an activated renin angiotensin system (RAS) causes
an imbalance between the vasoconstrictive and vasodilator mechanisms involving the …

… We also offer targeted therapy that may define how antioxidant therapy can either prevent
or … therapy targeting critical cytoprotective and aging pathways will provide more effective …

The myocardial Na + /H + exchange (NHE) represents a major mechanism for pH regulation
during normal physiological processes but especially during ischaemia and early …