… 19 years of age) are overweight or obese, 1 an increase of nearly … evidence that AT-infiltrating
macrophages (ATMs) play a … discuss macrophage biology and pathophysiology in obesity-…

… altered in differentially activated macrophages and link their … macrophage metabolism is
a promising target for therapeutic … While adipose tissue macrophages (ATM) represent less …

… These findings suggest that TREM2 acts as a novel regulator of adipogenesis and that
inhibiting TREM2 signaling may be a therapeutic target for obesity and IR. To fully understand the …

… macrophages as therapeutic targets, one needs to be discerning about the phenotype of
the macrophages targeted … M2-like macrophages could be targets of therapy for obesity-related …

… is used to pinpoint relevant future research directions to establish potential therapeutic targets
for shifting macrophage phenotype and function in order to promote adipose tissue health. …

… anti-inflammatory agents for obesity treatment highlights the need to re-… obesity to identify
more effective therapeutic targets. Local inflammation of adipose tissues can regulate obesity …

… emphasized the concept that macrophages can quickly adopt … signaling profiles in
macrophages during obesity-induced AT … tissue macrophage (ATM) biology in the setting of …

… between tumor-associated macrophage infiltration and tumor … of macrophages as an effective
therapeutic target. It remains to be deciphered to what extent adipose tissue macrophages …

… and metabolic activation in ATMs residing in obese adipose tissue is expected to lead to
novel therapeutic targets to curtail inflammatory responses that will ultimately reduce obesity-…

… and functions of macrophages in adipose tissue under conditions of obesity from three …
drug application. It is proposed that macrophages might be a key therapeutic target for obesity…