… the effects on the apoptotic pathway within the immune system is the topic of current
investigation. Prior to discussing the apoptotic pathway as a potential target for drug therapy, we will …

… the target cell in a given tissue/ organ to perceive these death receptor stimuli as either an
apoptotic… into the pathobiology of sepsis, but also suggests possible therapeutic targets for the …

… , represent an attractive therapeutic target for the septic patient. In the current review, we …
apoptotic pathways in sepsis syndrome and propose several potential therapeutic targets. …

… therapy targeted … apoptosis has the potential to be beneficial in sepsis regardless of the
source. Continued research into the use of siRNA antiapoptotic therapy in the treatment of sepsis …

… ER stress brings about abnormal apoptosis in sepsis animals, suggesting that ER … pathway
can serve as a novel diagnostic markers and effective therapeutic target for early stage sepsis…

… Recently was been found that pyroptosis is a unique form of proinflammatory programmed
death, that is different from apoptosis. A growing number of studies have investigated …

… signaling pathways, potential molecular mechanism, and pathway-associated therapy in
sepsis… Host-derived molecules interacting with activated cells possess pivotal role for sepsis …

… the lymphocyte in sepsis in controlling infection, it also illustrates a clear therapeutic target,
which might … Yet another target that decreases lymphocyte apoptosis is Akt, a regulator of cell …

… pathway dependent122. One of the hallmarks of sepsis is accumulated systemic apoptotic
… understanding, and may shed light on novel therapeutic targets for the treatment of sepsis. …

… successfully targeting both the appropriate signaling pathway and the specific cell population.
Blocking the circulating mediators or humoral factors during sepsis which induce apoptosis…