… might lead to a novel pharmacological therapy for cardiomyocytes apoptosis in sepsis. [53] …
in the apoptosis signaling pathway, may represent a new therapeutic target for patients with …

… pathway of sepsis has made the way for assignment of new drug targets in the therapy of
sepsis. This … novelties regarding our knowledge about sepsis published in the medical literature …

… Our laboratory has examined the effect of sepsis on endothelial cell apoptosis in a rat cecal
ligation and perforation model of sepsis. Rat thoracic aortas were obtained 24 hrs after cecal …

… mice and attenuates liver injury, inflammation, and apoptosis in the CLP septic model [105].
In the LPS-treated model, complete autophagic response is induced in hepatocytes [107, 108…

… intrinsic apoptotic pathway through … sepsis by periodical revisiting will additionally improve
our understanding toward delineating sepsis pathobiology and novel therapeutics targeting …

… laid on identifying novel therapeutic targets and prognostic biomarkers for sepsis treatment
to … , resulting in the increase of Bax/Bcl2 ratio and provocation of the apoptotic pathways (10). …

… C virus infection are associated with accelerated apoptosis. In … Also sepsis that is associated
with massive apoptosis of … activation of extrinsic and intrinsic apoptotic pathways has been …

… the inflammatory response and emphasizes the potential efficacy of PPARγ ligands as
novel therapeutic approaches beyond diabetes in sepsis, inflammation, and reperfusion injury. …

… is a relevant, novel therapeutic target in sepsis-associated with gram-negative bacterial
infection. … [68] administered VX-166, a broad caspase inhibitor which targets both apoptotic and …

… -induced and inflammatory mediator–induced apoptosis in severe sepsis. SIRT1 has
been shown to make the cells prone to TNF-α–induced apoptosis, by deacetylating the RelA/p65 …