Iron deficiency: an emerging therapeutic target in heart failure

A Cohen-Solal, C Leclercq, G Deray, S Lasocki… - Heart, 2014 - heart.bmj.com
… of Cardiology (ESC) defined iron deficiency in the context of … iron metabolism. The aim of
the present review is to summarise recent advances in iron deficiency pathophysiology and iron

Iron deficiency as a therapeutic target in cardiovascular disease

S Lakhal-Littleton - Pharmaceuticals, 2019 - mdpi.com
… of iron deficiency within the cardiovascular tissue have been demonstrated, highlighting
local iron deficiency as a new therapeutic target in these diseases. Some clinically used iron

Iron deficiency in pulmonary arterial hypertension: a potential therapeutic target

CJ Rhodes, J Wharton, L Howard… - European …, 2011 - Eur Respiratory Soc
… The prevalence and prognostic power of iron deficiency in IPAH patients indicates that it is
a potential therapeutic target. Dietary iron absorption may be repressed in these patients, and …

[PDF][PDF] Anemia and iron deficiency—new therapeutic targets in heart failure?

GW Dec - New England Journal of Medicine, 2009 - cardiacos.net
… ed that iron supplementation may be beneficial in patients who have iron deficiency and …
Two small, placebo-controlled trials of intravenous iron therapy in patients with heart failure …

Iron deficiency as therapeutic target in heart failure: a translational approach

C Bakogiannis, A Briasoulis, D Mouselimis… - Heart failure …, 2020 - Springer
… Thus, ID has presented as a promising therapeutic target for patients with HF. Iron contained
in hemoglobin is pivotal for tissue oxygenation. That said, this is but one of its uses in …

Iron deficiency as an emerging therapeutic target in patients stabilized after an episode of acute heart failure

M Tkaczyszyn, T Skrzypczak, J Michałowicz… - Cardiology …, 2021 - journals.viamedica.pl
… studies investigating iron deficiency (ID) in patients hospitalized for AHF indicate that this
comorbidity is more prevalent than in chronic heart failure, and iron status presents some …

Iron as a therapeutic target for Parkinson's disease

C Moreau, JA Duce, O Rascol… - Movement …, 2018 - Wiley Online Library
… Ferroptosis as a therapeutic target in Parkinson's disease. Alterations in the … ensures that
iron scavenged from cells is conserved and redeployed primarily to areas of iron deficiency. …

Hepcidin: a promising therapeutic target for iron disorders: a systematic review

J Liu, B Sun, H Yin, S Liu - Medicine, 2016 - journals.lww.com
… for iron disorder-associated diseases, the purpose of this review is to summarize the recent
findings on therapeutics targeting … from iron deficiency. Thalassemia major, a representative …

[HTML][HTML] Iron in fatty liver and in the metabolic syndrome: a promising therapeutic target

P Dongiovanni, AL Fracanzani, S Fargion, L Valenti - Journal of hepatology, 2011 - Elsevier
… the negative effect of iron overload, but that mild iron deficiency itself may further positively
impact on IR. Recently, our group has investigated the effect of iron depletion on glucose …

The hepcidin-ferroportin system as a therapeutic target in anemias and iron overload disorders

T Ganz, E Nemeth - Hematology 2010, the American Society of …, 2011 - ashpublications.org
… normal iron homeostasis and its disorders. The various approaches to therapeutic targeting
of hepcidin and ferroportin in iron-… and β-thalassemia) and iron-restrictive anemias (anemias …