… their implications in contemporary prostate cancer clinical care, as well as current efforts
in therapeutic targeting of AR-Vs aiming to overcome resistance to novel hormonal therapies. …

… The Hh signaling pathway has also been implicated as a potentially important therapeutic
target in cholangiocarcinoma 27,32 and our preliminary findings 5,33 suggested that …

… highlights a number of important new targets for therapeutic intervention. In contrast to earlier
… lead to the identification of a number of new therapeutic targets for tumour management. …

… Here, we discuss the significance of BCSC membrane biomarkers as potential prognostic
and therapeutic targets, reviewing the CSC-targeting therapies under clinical trials for breast …

… clinical trials based on c-MET molecular targets result in good safety profile and represent a
promising therapeutic … or in combination with other target drugs. Conclusion. The list of cell …

DNMT1 as a therapeutic target in pancreatic cancer: mechanisms and clinical implications | …
of the miR-148a/DNMT1 axis in PDAC indicates the potential of targeting DNMT1 for …

Introduction The development of therapeutic antibodies targeting immune checkpoint
molecules (ICMs) that induce long-term remissions in cancer patients has revolutionized cancer …

Recent microarray analyses showed that the S100 family contains members that are
candidate diagnostic markers or therapeutic targets. In the present study, to evaluate the …

… This review summarizes the role of HA in liver fibrosis at molecular levels as well as its
clinical implications and discusses the potential therapeutic uses of targeting HA in liver fibrosis. …

… in better understanding of molecular mechanisms and clinical implications of 20-HETE in …
These findings suggest that 20-HETE might be a new biomarker and a therapeutic target for …