Therapeutic targeting of the tumor microenvironment
L Bejarano, MJC Jordāo, JA Joyce - Cancer discovery, 2021 - AACR
… analysis of the current therapies targeting the TME, combining a discussion of the underlying
basic biology with clinical evaluation of different therapeutic approaches, and highlighting …
basic biology with clinical evaluation of different therapeutic approaches, and highlighting …
[PDF][PDF] Therapeutic targeting of the tumor microenvironment
JA Joyce - Cancer cell, 2005 - cell.com
… One advantage of therapies targeting the microenviron ment … stable, which is in contrast to
tumor cells that are known to be … to target different cell types in the tumor microenvironment, …
tumor cells that are known to be … to target different cell types in the tumor microenvironment, …
Targeting tumor microenvironment for cancer therapy
C Roma-Rodrigues, R Mendes, PV Baptista… - International journal of …, 2019 - mdpi.com
… The improvement in the efficacy of cancer therapeutics will probably be based on the use
of combined therapies targeting all cell populations that cohabit in the TME. Novel tactics can …
of combined therapies targeting all cell populations that cohabit in the TME. Novel tactics can …
Tumor microenvironment as a therapeutic target in cancer
Y Xiao, D Yu - Pharmacology & therapeutics, 2021 - Elsevier
… progress in targeting the tumor microenvironment in both … in targeting the tumor
microenvironment to achieve therapeutic … to better decipher the tumor microenvironment; and …
microenvironment to achieve therapeutic … to better decipher the tumor microenvironment; and …
Targeting the tumor microenvironment for cancer therapy
… setting the targeting of the tumor microenvironment to … the tumor stroma, and the similarity
with normal tissue present huge challenges for therapies targeting the tumor microenvironment…
with normal tissue present huge challenges for therapies targeting the tumor microenvironment…
[HTML][HTML] Targeting the tumor microenvironment
PA Kenny, GY Lee, MJ Bissell - … in bioscience: a journal and virtual …, 2007 - ncbi.nlm.nih.gov
… synthesized in the breast tumor microenvironment by a “druggable” target. The third-… therapy
targeted at a component in the microenvironment resulting in strong efficacy against tumors …
targeted at a component in the microenvironment resulting in strong efficacy against tumors …
Tumor microenvironment targeted nanotherapeutics for cancer therapy and diagnosis: A review
S Thakkar, D Sharma, K Kalia, RK Tekade - Acta biomaterialia, 2020 - Elsevier
… We highlight the potential of tumor microenvironment; its role in disease progression, …
effective cancer therapy by conceptual understanding of tumor microenvironment and epigenetic …
effective cancer therapy by conceptual understanding of tumor microenvironment and epigenetic …
Therapeutic targeting of MicroRNAs in the tumor microenvironment
R Raue, AC Frank, SN Syed, B Brüne - International journal of molecular …, 2021 - mdpi.com
… Their drug RGLS5579 aims to target miR-10b in glioblastoma multiforme, where it has been
identified as a promising therapeutic target [311]. In their current study, they aim to confirm …
identified as a promising therapeutic target [311]. In their current study, they aim to confirm …
The tumor microenvironment in hepatocellular carcinoma: current status and therapeutic targets
JD Yang, I Nakamura, LR Roberts - Seminars in cancer biology, 2011 - Elsevier
… each component of the tumor microenvironment and their roles in the pathogenesis of HCC.
In addition, we examine current treatments targeting the tumor microenvironment as well as …
In addition, we examine current treatments targeting the tumor microenvironment as well as …
[HTML][HTML] Underlying causes and therapeutic targeting of the inflammatory tumor microenvironment
EA Comen, RL Bowman, M Kleppe - Frontiers in cell and …, 2018 - frontiersin.org
… of tumor suppressors. In this review, we examine the concept of the tumor microenvironment
… response and the tumor microenvironment may shed light on new therapies for both primary …
… response and the tumor microenvironment may shed light on new therapies for both primary …
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