… and antagonists of adenosine receptors have been discovered, … the roles of the various
adenosine receptor subtypes, and in … of therapeutic application of adenosine receptor modulators …

Adenosine acts as a cytoprotective modulator in response to stress to an organ or tissue.
Although short-lived in the circulation, it can activate four subtypes of G protein-coupled …

… -expressed or deleted have now been created in attempts to elucidate the roles of all four
adenosine receptors. Various therapeutic targets for all the adenosine receptors are as follows: …

… Adenosine receptors are inhibited by caffeine and other methylxanthines and provide a
potential target for … into adenosine signaling in the CNS, 1–6,8 and on adenosine as a potential …

… Based on this discrepancy, we discuss the therapeutic potential of adenosine receptor …
in developing adenosine receptor ligands for specific clinical applications is that adenosine …

… If these data are related to the estimated potency of adenosine receptors we arrive at a picture
like that illustrated in Fig. 1. One can see that … Adenosine receptors as therapeutic targets …

… In contrast with other ARs, A 2B ARs have an antagonistic effect, which makes them
interesting as therapeutic targets. Kalla RV et al. categorized their antagonists as xanthine-based, …

… of physiologic and pathologic responses in many mammalian tissues by interacting with
at least four specific adenosine receptors (ARs) named A1, A2A, A2B, and A3 Citation[1-7]. …

… a general overview of adenosine receptors, covering aspects … on the multitude of roles that
adenosine has in dictating the … the therapeutic basis of harnessing the adenosine receptor …

… Significant advancement has been made in the understanding of the molecular pharmacology
and physiologic relevance of adenosine receptors, but our knowledge of A2B receptors …