Inflammation and cardiovascular disease: from pathogenesis to therapeutic target
E Golia, G Limongelli, F Natale, F Fimiani… - Current atherosclerosis …, 2014 - Springer
… the question of inflammation-guided therapy for cardiovascular risk prevention [44]. The
trial investigated whether statin therapy might affect cardiovascular risk in subjects with LDL …
trial investigated whether statin therapy might affect cardiovascular risk in subjects with LDL …
Cytokines as therapeutic targets to reduce cardiovascular risk in chronic inflammation
AM Miller, IB McInnes - Current pharmaceutical design, 2011 - ingentaconnect.com
… an increased atherosclerotic risk which cannot be explained by traditional cardiovascular
risk factors alone. Inflammatory pathways are implicated in this increased vascular risk. The …
risk factors alone. Inflammatory pathways are implicated in this increased vascular risk. The …
High-density lipoproteins: marker of cardiovascular risk and therapeutic target
PP Toth, MH Davidson - Journal of clinical lipidology, 2010 - Elsevier
… III for very high-risk patients, as HDL-C progressively decreases, risk for cardiovascular
events increases. Is simply driving LDL lower enough to optimize cardiovascular risk reduction? …
events increases. Is simply driving LDL lower enough to optimize cardiovascular risk reduction? …
Recent updates on novel therapeutic targets of cardiovascular diseases
M Afzal - Molecular and Cellular Biochemistry, 2021 - Springer
… in cardiac disorders treatment. The emphasis of this review will be on bringing recent
development in cardiac disorders from the discoveries of drug targets and their ligands. …
development in cardiac disorders from the discoveries of drug targets and their ligands. …
PPARs as therapeutic targets in cardiovascular disease
M van Bilsen, FA van Nieuwenhoven - … on therapeutic targets, 2010 - Taylor & Francis
… from cardiac disease. In 2010 the first analyses of the Action to Control Cardiovascular Risk
in … did not further increase the risk of cardiovascular events in type 2 diabetic patients at high …
in … did not further increase the risk of cardiovascular events in type 2 diabetic patients at high …
Hypofibrinolysis in diabetes: a therapeutic target for the reduction of cardiovascular risk
… therapies, questioning the safety of this approach. Therefore, to safely control thrombosis risk
… with the fibrin network representing a credible therapeutic target. In the current review, we …
… with the fibrin network representing a credible therapeutic target. In the current review, we …
Inflammatory related cardiovascular diseases: from molecular mechanisms to therapeutic targets
… cardiovascular events and worse prognosis in patients with CVD [9-13]. Curiously, they
might be important therapeutic targets … cholesterol are key therapeutic targets implemented to …
might be important therapeutic targets … cholesterol are key therapeutic targets implemented to …
NF-κB, A potential therapeutic target in cardiovascular diseases
W Cheng, C Cui, G Liu, C Ye, F Shao… - Cardiovascular Drugs …, 2023 - Springer
… Thus, NF-κB is a potential therapeutic target in the treatment of atherosclerosis and related
CVDs. Several biologics and small molecules as well as peptide/proteins have been shown …
CVDs. Several biologics and small molecules as well as peptide/proteins have been shown …
Cardiovascular risk
RA Payne - British journal of clinical pharmacology, 2012 - Wiley Online Library
… biomarkers may facilitate individualized drug treatment and provide new therapeutic targets.
… conventional risk factors. Nonetheless, they may offer exciting new therapeutic targets, as …
… conventional risk factors. Nonetheless, they may offer exciting new therapeutic targets, as …
Therapeutic approaches targeting inflammation for diabetes and associated cardiovascular risk
AB Goldfine, SE Shoelson - The Journal of clinical …, 2017 - Am Soc Clin Investig
… for weight and other risk factors (17, 18). Furthermore, the magnitude of cardiovascular risk
associated with CRP is similar in magnitude to that of traditional risk factors including systolic …
associated with CRP is similar in magnitude to that of traditional risk factors including systolic …
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