… therapeutic strategy to counteract the burden of cardio- and cerebrovascular disease. Being
… reported as markers of disease or interesting therapeutic targets in the cardiovascular field. …

… In summary, the Ser1177and Ser633 sites may be potential therapeutic target sites.
Regulating the phosphorylation of these two sites and the eNOS activation are regulatory …

… the current therapeutic strategies targeting pericytes for cerebrovascular diseases. Collectively,
this … about the use of pericytes as novel therapeutic targets for cerebrovascular diseases. …

… of cerebrovascular diseases … of cerebrovascular diseases and the pathological mechanism
of the NLRP3 inflammasome in aggravating atherosclerosis and cerebrovascular diseases. …

… pathways, manipulation of which may have therapeutic application in many NDs. This review
will … as emerging therapeutic targets for neurodegenerative and cerebrovascular diseases. …

… Cerebrovascular diseases (CVDs) are a group of pathological conditions that temporarily
or permanently affect the brain tissue mostly via the decrease of oxygen and glucose supply. …

… plays an essential role in cerebrovascular diseases. We introduce the … therapeutic avenues.
We suggest ways to resolve the vast inter-individual diversity of cerebrovascular disease …

… In this review, we summarize the state of the art regarding the P2X7 receptor role in
cerebrovascular damage and its possible use as a therapeutic target. In addition, we discuss its …

… to comment on the therapeutic areas that could be explored for potential indications. Therapeutics
… FXI/FXIa inhibition have the potential to usher in a new era of anticoagulation therapy. …

… However, gene therapy for the treatment of cerebrovascular disease is still in its infancy. To
date… of this therapeutic strategy for improving cerebrovascular endothelial function in disease. …