… widespread cardiovascular and cerebrovascular diseases, in particular… target for developing
new approaches to diagnostics and therapy of cardiovascular and cerebrovascular diseases…

… Cardio-cerebrovascular diseases (CCVDs) are characterized by ischemic or hemorrhagic
lesions of the heart, brain, and peripheral circulatory tissues (Liu Z. et al., 2018). It is the high …

… diseases (CVD) and ischemic cerebrovascular disease (ICD). … In this study, a multi-database,
in silico target identification, … As a pleiotropic drug with multi-target, carvedilol was set an …

… PAI-1, as the principal inhibitor of fibrinolysis, may play an important role in cerebrovascular
diseases by promoting vascular atherosclerosis and thrombosis. The presence of increased …

… Yet, another example is provided by the case of the blood–brain barrier (BBB), in which
interest as a therapeutic target has begun to grow. This interest is derivative of the role the BBB …

… diseases that are presently garnering significant attention [1], [2]. Cerebrovascular diseases
… There is an urgent need for new therapeutic targets and biomarkers that can predict the …

… collateral circulation, and its potential as a therapeutic target in ischaemic stroke. We focus
on … Finally, we present information about therapies that have been used to enhance collateral …

… Furthermore, the cerebrovascular degeneration and breakdown of the BBB in AD based on
… Furthermore, new roles of nanodrug delivery to treat AD and other therapeutic drug targets …

… cerebrovascular diseases. It contains nine sections: definitions, emergency assessment and
diagnosis, reperfusion therapy, antiplatelet therapy, … of ischaemic cerebrovascular disease, …

… that ACE2/Ang-(17)/Mas receptor axis has a role in the pathophysiology of ischemic stroke
and should be further investigated as a therapeutic target for cerebrovascular diseases [122]. …