… less toxic cancer therapies. Sensitive and specific biomarkers are critical tools for early
detection and monitoring of cancer, in addition to representing potential therapeutic targets. The …

… therapies. This review focusses on recent insights into the potential role of miRNAs both as
therapeutic targets … govern atherosclerosis and as clinical biomarkers that may be reflective of …

… with resistance to hormonal therapy. Experimental evidence … therapeutic target and a
predictive biomarker for ER+ breast cancer patients at high risk for resistance to hormonal therapy …

… biomarkers for CVD. Furthermore, miRNAs represent potential novel therapeutic targets for
… In addition, the use of miRNA as therapeutic targets is also discussed, as well as challenges …

… clinical targets, discuss the complexity surrounding their choice as such, and chronicle the
development strategies and outcomes of their clinical … included those biomarkers for which …

… have revealed promising therapeutic approaches via miRNA … biomarkers with diagnostic
and prognostic significance, but also as treatment response predictors and therapeutic targets …

… Of therapeutic relevance, these deregulated signal transduction components constitute
new potential biomarkers and therapeutic targets of great clinical interest for improving the …

… and have provided measurable clinical benefits to patients. In … miRNA as both a diagnostic
marker and a therapeutic target. … a predictive biomarker and a potential therapeutic target for …

… If so, ex-miRNA might provide a novel therapeutic target. … technological and clinical feasibility
of ex-miRNA as a biomarker. Further, to determine its potential as a therapeutic target, the …

… as therapeutic targets and biomarkers for prognosis. The inflammatory response to
ischemia changes with time, and knowing the timing of when these cytokines are increased or …