过去一年中添加的文章,按日期排序

Efficient Strategy to Discover DNA Aptamers Against Low Abundance Cell Surface Proteins in Scarce Samples

X Wu, Y Liu, D Zhang, J Yu, M Zhang… - Journal of the …, 2024 - ACS Publications
2 天前 - … Furthermore, we extend our aptamer selection to clinical … - and high-abundance
biomarkers without sample restriction. … discovering potential biomarkers in precision medicine. …

[HTML][HTML] EXTRACELLULAR VESICLE-DERIVED MIRNA AS NOVEL BIOMARKERS IN INTERSTITIAL LUNG DISEASE

C MUEGGE, L NGO, E NISSEN, K DONNELLY… - …, 2024 - journal.chestnet.org
2 天前 - … based on clinical and radiographic features. Identification of peripheral biomarkers
that … pathogenesis is appealing for diagnostic and therapeutic purposes. Given that these …

[HTML][HTML] … EXPLORING THE DEFINITION OF A DISEASE-MODIFYING THERAPY, AND THE DATA REQUIRED TO ESTABLISH A THERAPY AS DISEASE-MODIFYING …

V MCLAUGHLIN, RP FRANTZ, AR HEMNES… - …, 2024 - journal.chestnet.org
2 天前 - clinically relevant targets for DM in PAH due to their effects on hemodynamic
parameters and biomarkers. … treatments that target multiple pathways is clinically relevant for DM. …

[HTML][HTML] THE ANTIOXIDANT, ANTI-INFLAMMATORY, AND ATHEROSCLEROTIC ROLE OF MELATONIN IN PATIENTS WITH CHRONIC OBSTRUCTIVE …

LM PUIU, RMP NEMES, CM POP, E TABACU… - …, 2024 - journal.chestnet.org
2 天前 - … may be a valuable biomarker to assess inflammation and atherosclerosis, a risk
factor for cardiovascular events in COPD patients. TyG index is a clinical surrogate marker of …

The role of parvalbumin interneuron dysfunction across neurodegenerative dementias

CL Smeralda, S Pandit, S Turrini, J Reilly… - Ageing Research …, 2024 - Elsevier
2 天前 - … and differences among AD, FTD, and DLB, thus paving the way for identifying
novel biomarkers and potential therapeutic targets for the treatment of these diseases. …

Immune biomarkers and secondary hemophagocytic lymphohistiocytosis: a scoping review protocol

A Terrett, M Van Loo, K Sundararajan, D Brealey… - JBI Evidence … - journals.lww.com
2 天前 - biomarkers have been reported to represent potential therapeutic targets for the …
associated with patient outcomes may suggest new therapeutic targets for further investigation. …

Unveiling New Chapters in Medullary Thyroid Carcinoma Therapy: Advances in Molecular Genetics and Targeted Treatment Strategies

JX Huai, WH Zhang, Y Lou, G Wang, L Huang… - Frontiers in … - frontiersin.org
2 天前 - … the disease and revealing potential therapeutic targets. This … therapies, and the
identification of novel biomarkers. We also discuss the implications of these findings for clinical

[HTML][HTML] Essentiality of SLC7A11-mediated nonessential amino acids in MASLD

J Shen, E Xie, S Shen, Z Song, X Li, F Wang, J Min - Science Bulletin, 2024 - Elsevier
2 天前 - … that it might serve as a prognostic biomarker for MASLD in patients. These findings
… serine deficiency-triggered ferroptosis may provide a therapeutic target for its treatment. …

Unraveling the mysteries of MGMT: Implications for neuroendocrine tumors

J Xu, S Ji, X Yu, J Chen - Biochimica et Biophysica Acta (BBA)-Reviews …, 2024 - Elsevier
2 天前 - … MGMT regulation and summarize its clinical implications in NETs, which would help
establish the role of MGMT as a biomarker and its potential as a therapeutic target in NETs. …

Epigenetic Landscapes of Endometriosis: From Pathogenesis to Precision Medicine

A Więcek, A Bezubik, V Kananovich… - … . Folia Biologica et …, 2024 - czasopisma.uni.lodz.pl
2 天前 - … into disease mechanisms and therapeutic targets. Epigenetic … Biomarker studies
have identified specific miRNAs and … -invasive diagnosis and targeted therapies. siRNA-based …