… clinical effects of a therapy, we ideally need to conduct de novo MR studies of therapeutic
targets that modify the biomarker of interest. That is to say, MR analysis of drug targets is useful …

… and identifies emerging targets for HCC treatment. In addition, we introduce the development
of HCC drugs in China. Finally, we discuss potential problems in HCC drug therapy and …

… development of drugs that target specific pathways or mediators. In the future, we may need
to target … analyses of the responses obtained when assessing combinations of new drugs. …

… , particularly those targeted by recently reported or patented agents, provides useful clues
about how drug development has been focused on targets of specific disease classes. There …

… in multiple therapeutic contexts, but the modest response rate relative to preclinical expectations
underscores the need for extensive translational work to refine therapeutic hypotheses, …

… quest to identify novel targets for the rational development of antiinflammatory drugs. The
major … as likely targets for the development of novel antiinflammatory therapeutics. Preliminary …

… In this review, we highlight the emerging trends and approaches in protein drug
development by using examples of therapeutic proteins approved by the US Food and Drug …

… between genomics and drug development — one we argue will … relationship between genomics
and drug development. Next, … to influence both drug development and drug use. We end …

… an opportunity to uncover drugs that act in new ways and through new targets. Although …
and epileptogenesis, 31 suggesting that it could be a target for antiepileptogenic therapies. …

… medicine might help identify new therapeutic targets for vanilloids and avoid unwanted
actions. … medicine, which implies that they might generate new leads for drug development. …