Exosomal miRNAs as cancer biomarkers and therapeutic targets

A Thind, C Wilson - Journal of extracellular vesicles, 2016 - Taylor & Francis
… reflected by distinct exosomal miRNA (ex-miRNA) profiles isolated … miRNA as a cancer
biomarker and therapeutic target is critically analysed. Exosomes are a stable source of miRNA

Exosomal miRNAs in lung diseases: from biologic function to therapeutic targets

J Guiot, I Struman, E Louis, R Louis, M Malaise… - Journal of Clinical …, 2019 - mdpi.com
… the known and potential role of lung exosomes/exosomal miRNAs, in the maintaining of lung
… discuss using exosomes as prognostic/diagnostic biomarkers as well as therapeutic tools …

Exosomal miRNAs: biological properties and therapeutic potential

G Hu, KM Drescher, XM Chen - Frontiers in genetics, 2012 - frontiersin.org
… key to disease pathogenesis provides new insights into the development of therapeutic
targets in the treatment of human diseases, particularly for some forms of cancer. Currently, …

Exosomal microRNAs as biomarkers and therapeutic targets for hepatocellular carcinoma

A Sorop, D Constantinescu, F Cojocaru… - International Journal of …, 2021 - mdpi.com
… discuss miRNA’s correlation with the diagnosis and prognosis of HCC, either as single miRNA
… We also review the role of exosomal miRNAs in the tumourigenic process and in the cell …

Exosomal ncRNAs: Novel therapeutic target and biomarker for diabetic complications

YX Xu, SD Pu, X Li, ZW Yu, YT Zhang, XW Tong… - Pharmacological …, 2022 - Elsevier
… [54] This study demonstrated the potential role of these VEGF-related exosomal miRNAs
in retinal angiogenesis, which may be new tools for the treatment of DR in the future. These …

Exosomes: potential disease biomarkers and new therapeutic targets

MI Mosquera-Heredia, LC Morales, OM Vidal… - Biomedicines, 2021 - mdpi.com
… the regulatory mechanisms of exosome biogenesis, release … use as disease biomarkers and
therapeutic targets. In addition, … the involvement of some exosomal miRNAs and circRNAs in …

The roles of exosomal miRNAs and lncRNAs in lung diseases

Y Li, Z Yin, J Fan, S Zhang, W Yang - … transduction and targeted therapy, 2019 - nature.com
exosomal miRNAs or lncRNAs as therapeutic targets. Furthermore, exosomes used for
targeted therapy … avoid the recognition and removal of therapeutic exosomes by the individual’s …

Circulating microRNAs as biomarkers, therapeutic targets, and signaling molecules

SK Ajit - Sensors, 2012 - mdpi.com
… Identification of miRNAs in exosomesmiRNA targets hundreds of different mRNAs. Though
the authors do not reject the possibility that some miRNAs can be associated with exosomes, …

[HTML][HTML] Exosomal miRNAs in central nervous system diseases: biomarkers, pathological mediators, protective factors and therapeutic agents

X Xia, Y Wang, Y Huang, H Zhang, H Lu… - Progress in …, 2019 - Elsevier
… of exosomal miRNAs as potential diagnostic biomarkers, pathological regulators, and therapeutic
targets/… for the applications of exosomal miRNAs in the clinical setting is also provided. …

[HTML][HTML] Exosomes in atherosclerosis: performers, bystanders, biomarkers, and therapeutic targets

C Wang, Z Li, Y Liu, L Yuan - Theranostics, 2021 - ncbi.nlm.nih.gov
… Among the exosomal RNAs, miRNAs are the most abundant type 32 . Exosomal miRNAs
Similar to exosomal miRNAs, exosomal lncRNAs and circRNAs can also induce a series of …