Extracellular vesicles as biomarkers and therapeutic targets for cancer

F Urabe, N Kosaka, K Ito, T Kimura… - … of Physiology-Cell …, 2019 - journals.physiology.org
… they collect vesicles and carefully use the proper terms for the different small vesicles (31). …
for all kinds of small vesicles secreted in the extracellular space: exosomes, microvesicles, …

Extracellular vesicle-based therapeutics: Extracellular vesicles as therapeutic targets and agents

Y Takahashi, Y Takakura - Pharmacology & Therapeutics, 2023 - Elsevier
therapeutic targets for various diseases. However, an EV-based drug delivery system (DDS)
that utilizes its therapeutic … Moreover, the potential of using therapeutics targeting EVs has …

Extracellular vesicles in liver disease and potential as biomarkers and therapeutic targets

G Szabo, F Momen-Heravi - Nature reviews Gastroenterology & …, 2017 - nature.com
Extracellular vesicles (EVs) are membranous vesicles originating from different cells in the
… EVs are explored as biomarkers of disease and could also represent therapeutic targets and …

[HTML][HTML] Extracellular vesicles in cancer metastasis: Potential as therapeutic targets and materials

A Kogure, Y Yoshioka, T Ochiya - International journal of molecular …, 2020 - mdpi.com
… the subsequent release of these vesicles into the extracellular space. They are usually …
vesicles. In this review, we use the term EVs for all types of vesicles present in the extracellular

[HTML][HTML] On the choice of the extracellular vesicles for therapeutic purposes

C Campanella, C Caruso Bavisotto, M Logozzi… - International journal of …, 2019 - mdpi.com
Extracellular vesicles (EVs) are lipid membrane vesicles released … therapeutic molecules
within target cells. However, we do not know exactly which exosomes may be used in therapy

Extracellular vesicles as biomarkers and therapeutic targets in breast cancer

L Sadovska, J Eglītis, A Linē - Anticancer research, 2015 - ar.iiarjournals.org
Cancer-derived extracellular vesicles (EVs) contain various cancer-associated molecules, …
attention as cancer biomarkers and therapeutic targets. Unlike circulating tumor cells they are …

Extracellular vesicles in atherothrombosis: From biomarkers and precision medicine to therapeutic targets

L Badimon, T Padro, G Arderiu, G Vilahur… - Immunological …, 2022 - Wiley Online Library
Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of global
mortality. Extracellular vesicles (EVs) are small phospholipid vesicles that convey molecular …

Extracellular vesicles: biology and emerging therapeutic opportunities

S El Andaloussi, I Mäger, XO Breakefield… - Nature reviews Drug …, 2013 - nature.com
extracellular vesicle biology and the role of extracellular vesicles in disease, discuss emerging
therapeutic … and their components therefore represent a novel class of therapeutic targets. …

[HTML][HTML] Extracellular vesicles as tools and targets in therapy for diseases

MA Kumar, SK Baba, HQ Sadida… - … and targeted therapy, 2024 - nature.com
Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the extracellular
space. They exhibit diverse sizes, contents, and surface markers and are ubiquitously …

The therapeutic triad of extracellular vesicles: As drug targets, as drugs, and as drug carriers

M Moloudizargari, MH Asghari, A Goel - Biochemical pharmacology, 2021 - Elsevier
extracellular vesicles (EVs) has led to the accumulation of evidence on their critical roles in
various pathologies, as well as opportunities to design novel therapeutic … EVs for therapeutic