Identification of new therapeutic targets for prevention of CNS inflammation
T Owens - Expert opinion on therapeutic targets, 2002 - Taylor & Francis
… Animal experiments therefore point to IFN-γ and costimulatory microglia as logical targets
of therapy for MS. IFN-γ represents a more accessible target and should therefore be pursued …
of therapy for MS. IFN-γ represents a more accessible target and should therefore be pursued …
Caspases as therapeutic targets
B Howley, HO Fearnhead - Journal of cellular and molecular …, 2008 - Wiley Online Library
… disorders while focusing on caspase‐1 inhibition as a potential therapeutic strategy. Problems
facing the development of effective and safe caspase therapeutics will also be addressed. …
facing the development of effective and safe caspase therapeutics will also be addressed. …
[HTML][HTML] ABCA1 and ABCG1 as potential therapeutic targets for the prevention of atherosclerosis
M Matsuo - Journal of pharmacological sciences, 2022 - Elsevier
… , their increased activity may prevent Alzheimer's disease. … as therapeutic targets. This
review highlights that ABCA1 and ABCG1 could be potential therapeutic targets for preventing …
review highlights that ABCA1 and ABCG1 could be potential therapeutic targets for preventing …
High-density lipoproteins: a new potential therapeutic target for the prevention of cardiovascular disease
HB Brewer Jr - Arteriosclerosis, Thrombosis, and Vascular Biology, 2004 - Am Heart Assoc
… that raising HDL may represent an additional therapeutic target for prevention of CVD. …
Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. N …
Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. N …
Vascular inflammation as a therapeutic target for prevention of cardiovascular disease
LT Clark - Current Atherosclerosis Reports, 2002 - Springer
… under investigation that target the inflammatory process. … Some of the therapeutic targets
and scenarios currently … the identification of multiple new therapeutic targets. Inflammation is a …
and scenarios currently … the identification of multiple new therapeutic targets. Inflammation is a …
Novel therapeutic targets for prevention and therapy of sepsis associated acute kidney injury
CH Pelte, LS Chawla - Current drug targets, 2009 - ingentaconnect.com
… Many of these pathways offer attractive targets for current and novel therapeutic agents. …
which therapeutic intervention to deploy. Therefore, all of the potential therapeutic targets …
which therapeutic intervention to deploy. Therefore, all of the potential therapeutic targets …
[HTML][HTML] RNA binding protein as an emerging therapeutic target for cancer prevention and treatment
S Hong - Journal of cancer prevention, 2017 - ncbi.nlm.nih.gov
… effectors of RBPs as therapeutic target. For example, MYC is a target of many RBPs. It …
used as therapeutic target in cancer using mutant MYC or small molecule inhibitors.90–92 …
used as therapeutic target in cancer using mutant MYC or small molecule inhibitors.90–92 …
Cytokines are a therapeutic target for the prevention of inflammation-induced cancers
S Rose-John, H Schooltink - Cancer Prevention, 2007 - Springer
Interleukin-6 (IL-6) is an inflammatory cytokine with a well-documented role in cancer. The
cytokine binds to a membrane-bound IL-6 receptor (IL-6R) and this complex associates with …
cytokine binds to a membrane-bound IL-6 receptor (IL-6R) and this complex associates with …
Cellular and cytokine-based inflammatory processes as novel therapeutic targets for the prevention and treatment of atherosclerosis
PJ Little, A Chait, A Bobik - Pharmacology & therapeutics, 2011 - Elsevier
… persist as a therapeutic target of immense importance. Potential therapeutic targets include
the … the manner in which some of these inflammatory processes represent therapeutic targets. …
the … the manner in which some of these inflammatory processes represent therapeutic targets. …
Brain metastases as preventive and therapeutic targets
PS Steeg, KA Camphausen, QR Smith - Nature Reviews Cancer, 2011 - nature.com
… , the identification of BBB-permeable drugs with preventive or cytotoxic activity; and second,
… but effective therapeutics. Is the prevention of brain metastases a better drug target? …
… but effective therapeutics. Is the prevention of brain metastases a better drug target? …
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