… In recent years, new potential therapeutic targets that are involved in the pathogenesis of …
This Review analyses the new therapeutic targets (for example, ventricular remodelling, renin–…

Dysregulated proteolysis of the extracellular matrix of articular cartilage represents a unifying
hallmark of the arthritides, and has been a target for therapeutic intervention for some time, …

… in the exploration of therapeutic targets for the discovery of drugs … therapeutic targets and
to investigate the characteristics of these targets for providing useful clues to search new targets…

Alzheimer’s disease is a progressive neurodegenerative disease for which no cure exists.
There is a substantial need for new therapies that offer improved symptomatic benefit and …

… This makes STAT3 an attractive therapeutic target for cancers. Initial strategies aimed at
inhibiting STAT3 functions have focused on blocking the action of its activating kinases or …

A two-step strategy was developed consisting of differential display reverse transcriptase
polymerase chain reaction (DDRT-PCR) with cultured normal human fetal astrocytes and U-…

… The vulnerability of some cancer cells to oxidative signals is a therapeutic target for the rational
… of redox regulation in carcinogenesis and its potential as a therapeutic target is reviewed. …

… received the Orphan Drug Designation for the treatment of BPDCN. In conclusion, these …
an important therapeutic target for the treatment of BPDCN, while a possible in the treatment of …

… target for anticancer therapies and discuss the attractive prospect of manipulating this control
as a revolutionary strategy for cancer therapy. … as a novel target for anticancer therapy. …

… be involved in hepatic fibrosis and could represent a suitable therapeutic target [31]. Other
molecular targets have recently attracted much attention and specific modulators of some of …