… Additionally, we provide some updated potential therapeutic targets for the prevention or
treatment of ischemic AKI, including Toll-like receptors, adenosine receptors, and …

… Acute kidney injury (AKI) is a common clinical entity that is associated with high mortality …
kidney disease. Presently, no effective treatment for AKI is available, and novel therapeutic …

… Acute kidney injury (AKI) is a common disease with a … of chronic kidney disease and end
stage kidney failure. Preventing AKI … on Fyn kinase as a novel therapeutic target against AKI. …

… for tissue injury in all organs, boosting of the antioxidative Keap1- Nrf-2 system by activators
of Nrf-2 or Keap-1 inhibitors seem to be the most promising therapeutic target for prevention …

… platform for further investigation that could lead to identification of novel pathways and
potential therapeutic targets in different clinical settings, including AKI and other kidney diseases. …

… This reflects systemic iron overload with kidney injury. Recently, an analysis of the … kidney
replacement therapy (KRT) [41]. This study also highlighted the role of iron in kidney damage …

… Iron plays a key role in inducing cell death in acute kidney injury. Drugs targeting
ferroptosis and hepcidin are attractive targets to prevent and treat acute kidney injury (AKI). …

The current lack of complete understanding of the pathogenesis of acute kidney injury (AKI)
is a … We also discuss how to prevent the progression of chronic kidney disease (CKD) by …

… This review serves to update the topic of organ cross talk in AKI and focuses on potential
therapeutic targets to improve patient outcomes during AKI-associated multiple organ failure. …

… of Henle located in the renal medulla, are likely to be the primary location of injury in most
forms of AKI and hence, also represent one of the most important therapeutic targets for AKI. …