… been implicated in drug resistance in cancer. Importin and exportin inhibitors are being
considered as therapeutic targets against cancer and have shown preclinical anticancer activity. …

… early detection, prognostication and management of various cancers. Finally we explore
their potential therapeutic applications in the field of cancer and highlight some of the potential …

… targets tumor suppressors, including PDCD4. The potential for miR-21 as a therapeutic target
in lung cancer is … increased K-RAS driven lung cancer and that targeted deletion of miR-21 …

… evaluated as potential new drug targets to improve cancer therapy. This Review discusses
the potential use of cell cycle protein kinases as therapeutic targets for cancer, and provides a …

… MMPIs represent a totally different therapeutic modality from proven anti-cancer drugs and
thus … of MMPs as targets for therapeutic intervention in cancer. Keywords: MMP, MMPI, cancer, …

Since the initial discovery of the oncogenic activity of WNT1 in mouse mammary glands, our
appreciation for the complex roles for WNT signalling pathways in cancer has increased …

The cell cycle is controlled by numerous mechanisms ensuring correct cell division. This
review will focus on these mechanisms, ie regulation of cyclin‐dependent kinases (CDK) by …

… Given the central role of VEGF in tumor angiogenesis and the correlation with tumor growth,
VEGF has emerged as the most promising therapeutic target for angiogenesis inhibition. …

… to create therapeutic interventions for cancer management, … therapeutic targets for cancer
therapy. In addition, intimate interactions occur between parthanatos and other forms of cancer …

… We review here recent trends in targeting mitochondria in cancer. More specifically, we …
that target the mitochondria and are currently under investigation for different types of cancers (…