Cytokines as therapeutic targets in rheumatoid arthritis and other inflammatory diseases
S Siebert, A Tsoukas, J Robertson, I McInnes - Pharmacological reviews, 2015 - ASPET
… application of anticytokine therapies for other inflammatory diseases, particularly within the
… across diseases. Finally, we report on the current state of trials for newer therapeutic targets, …
… across diseases. Finally, we report on the current state of trials for newer therapeutic targets, …
miRNAs as therapeutic targets in inflammatory disease
Q Lu, R Wu, M Zhao, A Garcia-Gomez… - Trends in pharmacological …, 2019 - cell.com
… therapeutic targets in these diseases. In this review, by selecting several examples of
inflammatory diseases, … of certain miRNAs in these diseases, their targets, and the importance of …
inflammatory diseases, … of certain miRNAs in these diseases, their targets, and the importance of …
Toll-like receptors: promising therapeutic targets for inflammatory diseases
… diseases. In this review, we discuss the emerging role of TLRs in the pathogenesis of
inflammatory diseases and how targeting of TLRs offers a promising therapeutic strategy for the …
inflammatory diseases and how targeting of TLRs offers a promising therapeutic strategy for the …
Macrophage migration inhibitory factor: a therapeutic target across inflammatory diseases
… as a therapeutic target. Finally, MIF has a unique relationship with glucocorticoids, acting
to counter-regulate their anti-inflammatory effects, such that MIF antagonist therapy may be a …
to counter-regulate their anti-inflammatory effects, such that MIF antagonist therapy may be a …
The IL23/Th17 pathway as a therapeutic target in chronic inflammatory diseases
É Toussirot - … (Formerly Current Drug Targets-Inflammation & …, 2012 - ingentaconnect.com
… inflammatory diseases such as chronic joint diseases, inflammatory bowel diseases and
demyelinating diseases … as a relevant therapeutic target in autoimmune driven diseases, and …
demyelinating diseases … as a relevant therapeutic target in autoimmune driven diseases, and …
Cyclooxygenase-2 inhibitors as a therapeutic target in inflammatory diseases
MD Ferrer, C Busquets-Cortés, X Capó… - Current medicinal …, 2019 - ingentaconnect.com
… COX-2 is a suitable drug target against inflammatory diseases and tumorigenesis, because
it is the major contributor enzyme to prostanoid synthesis in inflammatory processes and its …
it is the major contributor enzyme to prostanoid synthesis in inflammatory processes and its …
[PDF][PDF] Osteoarthritis, an inflammatory disease: potential implication for the selection of new therapeutic targets
JP Pelletier, J Martel‐Pelletier… - Arthritis & Rheumatism …, 2001 - stem-art.com
… that have the potential to become therapeutic targets. These pathways can be modified to
effectively retard the progression of the disease. A number of such new agents, referred to as …
effectively retard the progression of the disease. A number of such new agents, referred to as …
New therapeutic target in inflammatory disease: macrophage migration inhibitory factor
EF Morand - Internal medicine journal, 2005 - Wiley Online Library
… inflammatory diseases rather than being disease-specific. This implies the need to identify
a therapeutic target which participates in the range of mechanisms operative in inflammation …
a therapeutic target which participates in the range of mechanisms operative in inflammation …
Inflammatory related cardiovascular diseases: from molecular mechanisms to therapeutic targets
… Curiously, they might be important therapeutic targets for patients with CVD [9-13]. This …
high-density lipoprotein cholesterol are key therapeutic targets implemented to reduce CVD rate [ …
high-density lipoprotein cholesterol are key therapeutic targets implemented to reduce CVD rate [ …
Signal transduction pathways and transcription factors as therapeutic targets in inflammatory disease: towards innovative antirheumatic therapy
SW Tas, PHJ Remans, KA Reedquist… - Current pharmaceutical …, 2005 - ingentaconnect.com
… arthritis (RA) as a prototype of inflammatory disease. … underlying RA and other chronic
inflammatory diseases. … offer the prospect of discovering new therapeutic targets. In this review we …
inflammatory diseases. … offer the prospect of discovering new therapeutic targets. In this review we …
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