… and therapeutic targets related to the inflammation associated with fatty liver diseases and
… Multiple cell types in the liver, including macrophages, neutrophils, other immune cell types …

… . Nuclear receptors as therapeutic targets in liver disease: are we there yet? Annu Rev
Pharmacol Toxicol 2016;56:605–26.doi:10.1146/annurev-pharmtox-010715-103209 pmid:http://…

… is an urgent need to develop new pathophysiology-oriented therapies. Recent translational
studies of human samples and animal models have identified promising therapeutic targets. …

… as well as in liver diseases and discuss the … and therapeutic targets for liver diseases, with
a focus on those miRNAs which are specifically expressed or enriched in several types of liver …

… Several cytokines have great therapeutic potential, and some are currently being tested as
therapeutic targets in clinical trials for the treatment of liver diseases, which are also described…

… therapies for the growing NAFLD epidemic. The data discussed in this article provide strong
… to think out of the box when considering novel therapeutic targets for patients with NAFLD. …

… EVs are explored as biomarkers of disease and could also represent therapeutic targets and
… of EVs in liver diseases and discuss their utility in biomarker discovery and therapeutics. …

… (104) Thus, the effects of FXR on NAFLD are complex and to date the role of FXR as a
therapeutic target for NASH has not been explored. However, this receptor is pharmacologically …

… Advances in our understanding of the pathophysiology of hepatic cystogenesis catalyzed
the search for new therapeutic targets. Most promising targets are described below and …

… All the changes that occur during liver injury alter metabolic functionality, aggravate liver
damage, and make PPARs important therapeutic targets for the treatment of these diseases [5]. …