[HTML][HTML] Many cytokines are very useful therapeutic targets in disease
M Feldmann - The Journal of clinical investigation, 2008 - Am Soc Clin Investig
… Rather, representative examples of the cytokines involved in some forms of cancer and … of
cytokines as therapeutic targets, and the overwhelming message is that “anti-cytokine medicine…
cytokines as therapeutic targets, and the overwhelming message is that “anti-cytokine medicine…
Cytokines as therapeutic targets in SLE
L Rönnblom, KB Elkon - Nature Reviews Rheumatology, 2010 - nature.com
… Many cytokine pathways of importance in the pathogenesis of systemic lupus erythematosus
(SLE) have been identified and clinical trials of biologic agents targeting a number of these …
(SLE) have been identified and clinical trials of biologic agents targeting a number of these …
Cytokines as therapeutic targets in rheumatoid arthritis and other inflammatory diseases
S Siebert, A Tsoukas, J Robertson, I McInnes - Pharmacological reviews, 2015 - ASPET
… Cytokines are therefore attractive therapeutic targets in these conditions. Anticytokine therapy
for … Finally, we report on the current state of trials for newer therapeutic targets, focusing …
for … Finally, we report on the current state of trials for newer therapeutic targets, focusing …
Historical review: cytokines as therapeutics and targets of therapeutics
J Vilček, M Feldmann - Trends in pharmacological sciences, 2004 - cell.com
… Cytokine research has spawned the introduction of new therapies that have revolutionized
the treatment of many … the introduction of cytokine and anti-cytokine therapies, with emphasis …
the treatment of many … the introduction of cytokine and anti-cytokine therapies, with emphasis …
IL-6 family cytokines: Key inflammatory mediators as biomarkers and potential therapeutic targets
N Unver, F McAllister - Cytokine & growth factor reviews, 2018 - Elsevier
… Chemoprevention targets many steps including tumor initiation, promotion and progression.
… the mechanism of Quercetin, a compound found in many plant-based foods, which has been …
… the mechanism of Quercetin, a compound found in many plant-based foods, which has been …
Therapeutic antibodies that target inflammatory cytokines in autoimmune diseases
Y Lai, C Dong - International immunology, 2016 - academic.oup.com
… cytokines regulates autoimmune diseases. On the basis of pre-clinical and clinical data, we
specifically discuss the therapeutic rationale for targeting these cytokines … that many new, …
specifically discuss the therapeutic rationale for targeting these cytokines … that many new, …
[HTML][HTML] Cytokine-modulating strategies and newer cytokine targets for arthritis therapy
SH Venkatesha, S Dudics, B Acharya… - International journal of …, 2014 - mdpi.com
… There are many small molecule inhibitors of cytokine production being tested besides those
… or more of these cytokine might offer a viable therapeutic target for arthritis therapy. Overall, …
… or more of these cytokine might offer a viable therapeutic target for arthritis therapy. Overall, …
[HTML][HTML] Inflammatory cytokines and chemokines as therapeutic targets in heart failure
A Hanna, NG Frangogiannis - Cardiovascular Drugs and Therapy, 2020 - Springer
… an attractive therapeutic target in many conditions associated … therapy for patients with
moderate to severe rheumatoid arthritis and temporal arteritis, and for the treatment of the cytokine …
moderate to severe rheumatoid arthritis and temporal arteritis, and for the treatment of the cytokine …
[HTML][HTML] Cytokines as therapeutic targets for cardio-and cerebrovascular diseases
… Mainly involved in fibrotic processes, TGF-β targets several cell types many of which are
deeply involved with high cardiovascular relevance: monocytes/macrophages, neutrophils, …
deeply involved with high cardiovascular relevance: monocytes/macrophages, neutrophils, …
Immunopathobiology and therapeutic targets related to cytokines in liver diseases
… Th1 cells can produce many cytokines that play important roles in the pathogenesis of liver
diseases (Fig. 1). Among them, both IFN-γ and TNFα have been extensively investigated over …
diseases (Fig. 1). Among them, both IFN-γ and TNFα have been extensively investigated over …
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