… targets for both antibody and small-molecule therapeutics has made them highly pursued
targets … led to novel discoveries regarding the mechanisms of resistance, which has defined a …

… the molecular mechanisms driving diabetic kidney disease to help identify new … of molecular
mechanisms that drive DKD pathogenesis is presented as a basis for advancing therapeutic …

… and other signaling molecules and connect extracellular events with intracellular signaling
cascades. Here, we review recent knowledge on the molecular mechanisms of drug and …

… given the diverse mechanisms of HCC development in humans. Accordingly, different
mouse HCC models should have similarly diverse and distinct molecular mechanisms. …

… molecular mechanisms linking activated MKK1 to the development of cardiac hypertrophy
in intact animals are not firmly established; however, there are several potential mechanisms …

… formation, pathogenic mechanisms underlying diabetes … molecular mechanisms that regulate
cell survival and apoptosis of retinal cells and discuss new and exciting therapeutic targets …

… more effective therapeutics. This review summarizes recent molecular mechanisms and …
and discusses the potential of identifying specific molecules against tumor cells or tumor …

… Morever, we discuss Sirtuins 1 and 3 as a therapeutic target for counteracting diabetes-induced
oxidative stress and glomerular injury. The role of the developmental pathways Notch1 …

… therapies for high-risk patients. Here we discuss the potential of developing targeted therapies
against aberrantly expressed molecules … and how these selected targets can be drugged …

… therapeutic interventions, focusing on molecules that link oxidative stress to inflammation to
provide potential therapeutic targets for … changes and the molecular events under diabetic …