Therapeutic targets for rheumatoid arthritis: Progress and promises
A Alghasham, Z Rasheed - Autoimmunity, 2014 - Taylor & Francis
… Of these, strategies that target RAGE and its associated signaling events in our … therapeutic
target for RA. However, there remains a significant unmet clinical need for new therapies as …
target for RA. However, there remains a significant unmet clinical need for new therapies as …
Histone deacetylases as new therapeutic targets in triple-negative breast cancer: Progress and promises
N Garmpis, C Damaskos, A Garmpi… - Cancer Genomics & …, 2017 - cgp.iiarjournals.org
… It is essential to find new therapies against TNBC, in order to surpass the resistance and …
therapies. Given the fact that epigenetic processes control both the initiation and progression of …
therapies. Given the fact that epigenetic processes control both the initiation and progression of …
From biomarkers to therapeutic targets—the promises and perils of long non-coding RNAs in cancer
… they are emerging as potent regulators of tumor progression and metastasis. Here, we will
… progression or therapy response and which might represent promising therapeutic targets. …
… progression or therapy response and which might represent promising therapeutic targets. …
Molecular therapeutics: promise and challenges
EC Kohn, Y Lu, H Wang, Q Yu, S Yu, H Hall… - Seminars in …, 2004 - Elsevier
… For a molecule to be a therapeutic target, it must play an active … progression may not be an
appropriate target. The best evidence that a molecule is playing a role in tumor progression at …
appropriate target. The best evidence that a molecule is playing a role in tumor progression at …
TGF-β as a therapeutic target in high grade gliomas–promises and challenges
JV Joseph, V Balasubramaniyan, A Walenkamp… - Biochemical …, 2013 - Elsevier
… functions during cancer progression, in a wide range of cancers. Here, we review the tumor
promoting function of TGF-β and its possible promise as a therapeutic target in high grade …
promoting function of TGF-β and its possible promise as a therapeutic target in high grade …
The Promise of Progress: Emerging Drug Targets and Advanced Therapies
A Kumar - International Journal of Pharmaceutical and Healthcare …, 2023 - ijphi.com
… targets are crucial to the advancement of therapeutic methods. The development of new
therapeutic targets has … heavily on traditional medication targets. To gain a handle on these new …
therapeutic targets has … heavily on traditional medication targets. To gain a handle on these new …
[HTML][HTML] RNA biology provides new therapeutic targets for human disease
LW Harries - Frontiers in genetics, 2019 - frontiersin.org
… Although these approaches show promise, to date most remain some distance from the …
The RNA epigenomic writers and erasers are therefore promising future therapeutic targets. At …
The RNA epigenomic writers and erasers are therefore promising future therapeutic targets. At …
Promises and challenges of MicroRNA-based treatment of multiple myeloma
… an effective miRNA-based therapy still includes the … -target effects [9]. In this light, the present
review reports and discusses the potential anti-tumour activity of miRNAs and their promise …
review reports and discusses the potential anti-tumour activity of miRNAs and their promise …
Rac1 as a therapeutic anticancer target: Promises and limitations
C Bailly, J Beignet, G Loirand, V Sauzeau - Biochemical pharmacology, 2022 - Elsevier
… which promotes malignant transformation and tumor progression [32], [33]. This alternative
splice variant is considered as a potential therapeutic target for improving the clinical efficacy …
splice variant is considered as a potential therapeutic target for improving the clinical efficacy …
[HTML][HTML] Where we stand with precision therapeutics in myeloma: prosperity, promises, and pipedreams
… mutated pathways that may serve as additional therapeutic targets (2). Furthermore, the use
of … hold the promise of finally incorporating this valuable genomic data to target appropriate …
of … hold the promise of finally incorporating this valuable genomic data to target appropriate …
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