… Here, we will highlight prime examples of lncRNAs that serve as marker for cancer
progression or therapy response and which might represent promising therapeutic targets. …

… of powerful therapeutic strategies to treat these diseases. In contrast to conventional therapies
that … are more akin to targeted therapies because they are mechanistically driven and are …

Introduction: Research over the past three decades has identified p53 as a multi-functional
transcription factor. p53 influences myriad, highly diverse cellular processes, and represents …

… enrich the catalogue of therapeutic targets, the task of developing therapies suitable for
successful … Yet, the success of therapies that target specific oncoproteins in molecularly defined …

… itaconate production in resident macrophages remain to be determined, this metabolite
facilitates tumor progression in the peritoneal cavity and may represent a novel therapeutic target …

… of ‘targeted’ therapy in ovarian cancer will focus on molecular targets of documented relevance
… However, the relevance of HER-2 as a molecular therapeutic target in epithelial ovarian …

… Histone deacetylases (HDACs) represent emerging therapeutic targets in the context of …
However, the translation of such therapeutic approach to clinics has been only marginally …

… deacetylase 8 (HDCA8), a zinc-dependent HDAC subtype, as potential therapeutic target for
FD. … HDAC8, a potential therapeutic target, regulates proliferation and differentiation of bone …

… function and discover therapeutic targets. Chemical probe off-targets are a confounding factor
as the observed phenotype may be driven by inhibition of an unknown off-target instead of …

… promise that the therapeutic benefits of NSAIDs could be optimized through inhibition of
COX‐2, while minimizing their adverse side effect profile associated with inhibition of COX‐1. …