HTLV-1, the other pathogenic yet neglected human retrovirus: from transmission to therapeutic treatment

N Futsch, R Mahieux, H Dutartre - Viruses, 2017 - mdpi.com
HTLV-1-infected people do not benefit from such efficient therapies yet: only symptomatic
individuals are treated… of HTLV-1 viral transmission, HTLV-1-linked symptoms and their current …

Antiretroviral therapy in HTLV-1 infection: an updated overview

F Marino-Merlo, E Balestrieri, C Matteucci, A Mastino… - Pathogens, 2020 - mdpi.com
… of antiretrovirals in HTLV-1 infection compared with HIV infection. Thus, given that the
opportunity to treat HTLV-1 infected individuals with antiretroviral therapy is still controversial, in …

Inflammatory manifestations of HTLV-1 and their therapeutic options

F Martin, GP Taylor, S Jacobson - Expert review of clinical …, 2014 - Taylor & Francis
… aspects of HTLV-1 infection: HAM/TSP, HTLV-1 associated uveitis, HTLV-1 associated …
In the absence of effective antiretroviral therapy for HTLV-1, current treatments target the by-…

Biology and treatment of HTLV-1 associated T-cell lymphomas

K Tsukasaki, K Tobinai - Best Practice & Research Clinical Haematology, 2013 - Elsevier
… , the decision process to select the therapeutic modality for each patient and the possibility
of interference with OS by second-line treatment remains unknown. A prospective multicenter …

A novel therapeutic molecule against HTLV-1 infection targeting provirus

A Tanaka, S Takeda, R Kariya, K Matsuda, E Urano… - Leukemia, 2013 - nature.com
… Taken together, these data show that ZFN is an attractive therapeutic molecule for treating
HTLV-1 infection, and may form the basis of a treatment that eliminates the virus from infected …

Reducing the global burden of HTLV-1 infection: an agenda for research and action

L Willems, H Hasegawa, R Accolla, C Bangham… - Antiviral research, 2017 - Elsevier
… of prevention and treatment of HTLV-1 infection and promote basic research. HTLV-1 is the
… that impair the development of efficient therapies against HTLV-1-induced diseases are the …

How to Control HTLV-1-Associated Diseases: Preventing de Novo Cellular Infection Using Antiviral Therapy

A Pasquier, S Alais, L Roux, MI Thoulouze… - Frontiers in …, 2018 - frontiersin.org
… There is a strong correlation between HTLV-1 proviral load (PVL) and clinical status of … to
prevent or treat HTLV-1-associated diseases among carriers. Treatment of ATLL patients using …

HTLV-1 infections

CRM Bangham - Journal of clinical pathology, 2000 - jcp.bmj.com
… Human T lymphotropic virus type 1 (HTLV-1) causes disabling and fatal diseases, yet there
… There is no treatment of proved value in HAM/TSP. Drugs used in informal therapeutic trials …

HTLV-1 and apoptosis: role in cellular transformation and recent advances in therapeutic approaches

JM Taylor, C Nicot - Apoptosis, 2008 - Springer
… T cells against conventional therapies and the immuno-… HTLV-1 to counteract cellular
death pathways remains an important challenge for future therapies and the treatment of HTLV-1

Roles of HTLV-1 basic zip factor (HBZ) in viral chronicity and leukemic transformation. Potential new therapeutic approaches to prevent and treat HTLV-1-related …

JM Mesnard, B Barbeau, R Césaire, JM Péloponèse - Viruses, 2015 - mdpi.com
… Thirteen year ago, we first reported that the minus strand of HTLV-1 encoded for a basic Zip
HTLV-1 research on new therapeutic approaches to treat HTLV-1-related human diseases. …