… treatment for human T-cell leukemia virus type 1 (HTLV-1)… therapy—interferon-α, valproic
acid, and prednisolone—on clinical outcomes, main HTLV-1 viral factors, and host anti-HTLV-1 …

… and response to initial therapy. Intensive … 1 prior case series of patients with ATL treated
over 20 years ago used localized external beam radiotherapy. We report a patient series treated …

… of HTLV-1 infected individuals is observed [20,21]. However, the drugs developed for treating
HIV infection are not effective for treating HTLV-1-… achievements in therapeutic targeting of …

… Then, starting from the therapeutic protocols currently used in the treatment of each of
these … HTLV-1 infection treatments can interact with antiretroviral therapies used in HIV-1/HTLV-1 …

… Moreover, the treatment of HAM/TSP remains highly … -modifying therapies are widely used,
their value is unproved. At present, clinical management is focused on symptomatic treatment …

… Programmed cell death-1 (PD-1) signaling pathway, one of the most … 1 signaling pathway
in HTLV-1 infection as well as its application as a novel approach for treatment of HTLV-1 …

… HTLV-1 replication. The recent advances help to provide further reason for hope in effective
therapeutic options for HTLV-1-… therapeutic intervention for the treatment of HTLV-1 infection. …

… by human T-cell leukemia virus type 1 (HTLV-1). We retrospectively analyzed 195 patients
with … The median survival for patients treated with modern therapies between 2000 and 2016 …

… therapeutic targets and repurposing existing drugs. These advances are crucial in developing
more effective and targeted treatments against HTLV-1 … therapy than those without HTLV-1 …

… Of note, we have shown in this study that patients reached therapeutic levels of As2O3 (1
mM) slowly, while the disease was rapidly progressing. Future studies should now evaluate the …