Stroke: Molecular mechanisms and therapies: Update on recent developments

F Shehjar, B Maktabi, ZA Rahman, GA Bahader… - Neurochemistry …, 2023 - Elsevier
… The molecular mechanisms involved in the pathophysiology are essential to understanding
targeted drug development. Some common mechanisms are excitotoxicity and calcium …

Molecular mechanisms of inflammation in sarcopenia: diagnosis and therapeutic update

GE Jimenez-Gutierrez, LE Martínez-Gómez… - Cells, 2022 - mdpi.com
… Research to find the precise molecular mechanisms implicated in this condition can
increase knowledge for the better prevention, diagnosis, and treatment of sarcopenia. Our work …

[HTML][HTML] Doxorubicin-induced cardiotoxicity: An update on the molecular mechanism and novel therapeutic strategies for effective management

PS Rawat, A Jaiswal, A Khurana, JS Bhatti… - Biomedicine & …, 2021 - Elsevier
… a detailed update on the current understanding of the pathological mechanisms behind the
well-… Herein, we have compiled detailed molecular mechanisms which are involved in Dox-…

Recent updates on novel therapeutic targets of cardiovascular diseases

M Afzal - Molecular and Cellular Biochemistry, 2021 - Springer
… and also to understand and explore the molecular mechanism of disease development.
The establishment of drug from new lead molecules is based on advances in basic science of …

Molecular mechanism and therapeutic modulation of high mobility group box 1 release and action: an updated review

B Lu, C Wang, M Wang, W Li, F Chen… - Expert review of …, 2014 - Taylor & Francis
molecular mechanisms underlying the regulation of pathogen-associated molecular patterns
(PAMPs)-induced HMGB1 secretion, and summarize many HMGB1-targeting therapeutic

Gut inflammation: current update on pathophysiology, molecular mechanism and pharmacological treatment modalities

K Gyires, E Viktoria Toth… - Current pharmaceutical …, 2014 - ingentaconnect.com
… Based on extensive research over the last decade, besides the conventional therapy,
there are several novel pathways and specific targets, on which focus new therapeutics. New …

Cellular and molecular mechanisms of hepatocellular carcinoma: an update

RN Aravalli, ENK Cressman, CJ Steer - Archives of toxicology, 2013 - Springer
molecular events to facilitate tumor initiation, progression, and metastasis. The emergence
of microRNAs and molecular-targeted therapies … processes and molecular mechanisms that …

[HTML][HTML] Alkylphospholipids: An update on molecular mechanisms and clinical relevance

P Rios-Marco, C Marco, X Gálvez… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Molecular mechanisms of anticancer activity of these compounds have been … updates the
main APL applications investigated so far and the ongoing evaluation of action mechanisms

HIV-1 latency: an update of molecular mechanisms and therapeutic strategies

A Battistini, M Sgarbanti - Viruses, 2014 - mdpi.com
… , and although the mechanisms that lead to HIV-1 latency in CD4 + T cells are still not
completely understood, a number of different cellular and molecular mechanisms, that contribute to …

An update on the role of Nrf2 in respiratory disease: molecular mechanisms and therapeutic approaches

J Lee, J Jang, SM Park, SR Yang - International Journal of Molecular …, 2021 - mdpi.com
Nuclear factor erythroid 2-related factor (Nrf2) is a transcriptional activator of the cell protection
gene that binds to the antioxidant response element (ARE). Therefore, Nrf2 protects cells …