Main clinical features of COVID-19 and potential prognostic and therapeutic value of the microbiota in SARS-CoV-2 infections

Y He, J Wang, F Li, Y Shi - Frontiers in Microbiology, 2020 - frontiersin.org
… main clinical features of COVID-19 and potential role of microbiota in COVID-19. SARS-CoV …
COVID-19 share similar clinical features, although the estimated fatality rate of COVID-19 is …

Therapeutic strategies for COVID-19: progress and lessons learned

G Li, R Hilgenfeld, R Whitley, E De Clercq - Nature Reviews Drug …, 2023 - nature.com
… anti-coronavirus activities. We also discuss the lessons learned from COVID-19 and other
infectious diseases with regard to drug repurposing strategies, pan-coronavirus drug targets, …

Diagnostic, prognostic, and therapeutic value of droplet digital PCR (ddPCR) in COVID-19 patients: a systematic review

A Ishak, MM AlRawashdeh, SM Esagian… - Journal of clinical …, 2021 - mdpi.com
… This study aimed to assess the diagnostic, prognostic, and therapeutic value of ddPCR in
COVID-19 patients, regardless of the sample type. It also aimed to compare the diagnostic …

Potential therapeutic value of dexmedetomidine in COVID-19 patients admitted to ICU

H Zhao, R Davies, D Ma - British Journal of Anaesthesia, 2021 - bjanaesthesia.org
… as a novel therapeutic strategy to attenuate the vital organ injuries in COVID-19 (Fig. 1),
whilst simultaneously providing beneficial sedative effects to enable oxygen therapy via either …

Therapeutic and prognostic role of vitamin D for COVID-19 infection: A systematic review and meta-analysis of 43 observational studies

F Petrelli, A Luciani, G Perego, G Dognini… - The Journal of steroid …, 2021 - Elsevier
… vitamin D values, risk of COVID-19 infection was higher compared to those with replete values
(OR = … Reduced vitamin D values resulted in a higher infection risk, mortality and severity …

CoViTris2020 and ChloViD2020: a striking new hope in COVID-19 therapy

AM Rabie - Molecular Diversity, 2021 - Springer
values of 0.31 (according to the used anti-COVID-19 assay, CoViTris2020 is the most potent
SARS-CoV-2 inhibitor discovered till now) and 1.01 μM, and amazingly presented about 65-…

Potential diagnostics and therapeutic approaches in COVID-19

P Kumari, A Singh, MR Ngasainao, I Shakeel… - Clinica Chimica …, 2020 - Elsevier
… Having a comprehensive knowledge of the diagnostic approaches of SARS-CoV-2, and
its pathogenesis will be of great value in designing a long-term strategy to tackle COVID-19. …

Therapeutic advances in COVID-19

N Murakami, R Hayden, T Hills, H Al-Samkari… - Nature Reviews …, 2023 - nature.com
… , we discuss the therapeutic advances in the treatment of COVID-19 since the … therapy (KRT),
as well as kidney transplant recipients, who are all at increased risk of adverse COVID-19

Therapeutic targets and potential agents for the treatment of COVID19

Y Wu, Z Li, YS Zhao, YY Huang… - Medicinal Research …, 2021 - Wiley Online Library
… Montelukast sodium and maribavir, proposed as potential candidate treatments for patients
with COVID-19, 102 showed IC 50 values of 7.3 and 20 μM against SARS-CoV-2 M pro , …

Trends in COVID-19 therapeutic clinical trials.

K Bugin, J Woodcock - Nature Reviews Drug Discovery, 2021 - go.gale.com
… 2 | Trials of COVID-19 drug candidates that may be … We chose threshold values of enrolment
in consideration of … that approximately 5% of the total COVID-19 trial arms in our assessment …