Type 1 diabetes (T1D) is caused by autoimmune destruction of insulin-producing β cells
located in the endocrine pancreas in areas known as islets of Langerhans. The current standard…

… of patients with type 1 diabetes, 4 13% had a glycated hemoglobin level of less than 7%. …
in patients with type 1 diabetes, and 35 to 40% of patients with type 1 diabetes regularly have …

Over the past decade, knowledge of the pathogenesis and natural history of type 1 diabetes
has grown substantially, particularly with regard to disease prediction and heterogeneity, …

… Such genes could serve in gene therapy of diabetes. However, both preventive strategies …
to type 1 diabetes, before damage to β cells has occurred. In addition, gene therapy awaits the …

… some insulin) after the clinical onset and initiation of insulin therapy are not understood 111
. Whether the insulin therapy has dampened the inflammatory process at the time of clinical …

The use of stem cells in regenerative medicine holds great promise for the cure of many
diseases, including type 1 diabetes mellitus (T1DM). Any potential stem-cell-based cure for …

… Here, we review insulin management options and strategies in nonpregnant adult patients
with type 1 diabetes mellitus (T1DM). Most patients with T1DM should follow a regimen of …

… In conclusion, in patients with type 1 diabetes with suboptimal glycemic control, the use of
a sensor-augmented insulin pump was associated with significant improvement in glycated …

… accounts for only about 5–10% of all cases of diabetes; however, its incidence continues
to increase worldwide and it has serious short-term and long-term implications. The disorder …

… of type 1 diabetes stages. In this new paradigm, a preclinical stage 1 case of type 1 diabetes
is … from abnormal glycaemia to overt diabetes, diagnosed by standard criteria (figure 2B). …