… understood, modulate the sensitivity of tumor cells to specific targeted drugs. These factors
… to assess the responsiveness of tumor cells to therapy. Gene expression profiling using …

… cell populations that promote tumor escape from immune surveillance and metastasis.
Therapeutic approaches that kill tumor cells … are becoming an established therapeutic option, but …

… therapeutic response has considerably increased. This expanded knowledge of tumor
cell plasticity contributes to developing novel therapeutic strategies or combination therapy …

… tumor cells to stromal fibroblasts or to components of the extracellular matrix can also blunt
therapeutic response… on how the TME regulates therapeutic response and discuss potential …

… cell states, the mechanisms governing cell plasticity and their impact on tumor progression,
metastasis and therapy response… Understanding the mechanisms involved in cancer cell …

… for their activity against tumors. We undertook the current study to examine how tumor cell
responses to IFNγ affect the antitumor activity of IL-12. IFNγ stimulates cells by binding to a …

… of tumor cell death and/or the immune system can be manipulated so dying tumor cells …
as part of a combination therapy, eg, CD40L), we might achieve effective T-cell activation. …

… in tumor cells as an adaptive response to the hypoxia caused by antiangiogenic therapy can
be expanded to determine the effect of hypoxia on cells in the tumor microenvironment. For …

… and cons of different methods for primary tumor cell culture. … cons of different methods for
primary tumor cell culture. Furthermore, … primary tumor cells redefine cancer therapies with high …

… circulating tumor cell detection as a tool to monitor therapy in … about the frequency of circulating
tumor cells in patients with … characteristics of circulating tumor cells are largely unknown. …