Thermosensitive hydrogels as scaffolds for cartilage tissue engineering

Y Zhang, J Yu, K Ren, J Zuo, J Ding… - Biomacromolecules, 2019 - ACS Publications
… sol–gel transition and easily forms seed cell-loaded scaffold for cartilage repair. In this …
the performance of different types of thermosensitive hydrogels for cartilage repair (Table 1). …

Thermosensitive chitosan–Pluronic hydrogel as an injectable cell delivery carrier for cartilage regeneration

KM Park, SY Lee, YK Joung, JS Na, MC Lee, KD Park - Acta biomaterialia, 2009 - Elsevier
… for articular cartilage regeneration. In this study, a thermosensitive chitosan–Pluronic (CP)
hydrogel was designed as an injectable cell delivery carrier for cartilage regeneration. The CP …

A moldable thermosensitive hydroxypropyl chitin hydrogel for 3D cartilage regeneration in vitro and in vivo

Y Xu, Y Xu, B Bi, M Hou, L Yao, Q Du, A He, Y Liu… - Acta Biomaterialia, 2020 - Elsevier
… However, to date, in vitro cartilage regeneration based on hydrogel has not achieved …
cartilage regeneration based on a moldable thermosensitive hydroxypropyl chitin (HPCH) hydrogel

Thermosensitive hydrogel for cartilage regeneration via synergistic delivery of SDF-1α like polypeptides and kartogenin

X Yuan, J Wan, Y Yang, L Huang, C Zhou, J Su… - Carbohydrate …, 2023 - Elsevier
Regeneration of injured articular cartilage is limited by low … Hydrogels are widely used
to repair cartilage because they … -loaded thermosensitive hydroxypropyl chitin hydrogel (HPCH) …

ECM based injectable thermo-sensitive hydrogel on the recovery of injured cartilage induced by osteoarthritis

Y Li, J Cao, S Han, Y Liang, T Zhang… - Artificial cells …, 2018 - Taylor & Francis
… , we developed an intra-articular injection thermo-sensitive gel delivery system, which bone
… application as repair of cartilage damage in OA ( Scheme 1 ). In bone regeneration studies, …

Component effect of stem cell-loaded thermosensitive polypeptide hydrogels on cartilage repair

H Liu, Y Cheng, J Chen, F Chang, J Wang, J Ding… - Acta biomaterialia, 2018 - Elsevier
… The contents of GAGs and Col II in the regenerated cartilage and normal cartilage were …
cartilage repair capabilities of thermosensitive hydrogels. The GAGs contents of regenerated

Thermoreversible hydrogel scaffolds for articular cartilage engineering

JP Fisher, S Jo, AG Mikos… - Journal of Biomedical …, 2004 - Wiley Online Library
… We have investigated the use of a temperature-sensitive hydrogel for the delivery of … a
means for cartilage repair. The objectives of this work were to determine the effects of (1) hydrogel

The recent advancement in the chitosan-based thermosensitive hydrogel for tissue regeneration

A Abdollahi, A Malek-Khatabi, MS Razavi… - Journal of Drug Delivery …, 2023 - Elsevier
… to spontaneously regenerate and self-repair under appropriate … thermosensitive hydrogel
that have been reported for the treatment of bone damages and bone tissue regeneration

Development and characterization of carbohydrate-based thermosensitive hydrogels for cartilage tissue engineering

CB Westin, MHT Nagahara, MC Decarli, DJ Kelly… - European Polymer …, 2020 - Elsevier
… Besides polymer type, the choice of drugs to be incorporated in injectable hydrogel formulations
designed for cartilage tissue repair is of paramount importance. Bioactive agents such …

Thermosensitive hydrogel loaded with primary chondrocyte-derived exosomes promotes cartilage repair by regulating macrophage polarization in osteoarthritis

X Sang, X Zhao, L Yan, X Jin, X Wang, J Wang… - … and regenerative …, 2022 - Springer
… In this study, a thermosensitive, injectable hydrogel was prepared by in situ crosslinking of …
cartilage destruction in OA, we investigated the effects of exosomes encapsulated in hydrogel