… in the early days of radiotherapy is now rarely seen (3). Nonetheless, the excess incidence
of heart failure in patients who have received chest irradiation persists to current times and is …

… The same group found strain-dependent variation in radiation-induced interleukin (IL)-1α,
IL-1β, and tumor necrosis factor (TNF)-α mRNA levels and suggested roles for these cytokines …

… -α), interleukin-1α (IL-1α) and IL-1β mRNA expression are altered acutely after irradiation,
during … to radiation. Fibrosis-sensitive (C57BL/6) and fibrosis-resistant (C3H/HeJ) mice were …

… A similar pattern was reproduced in Apoe−/− mouse 10 weeks after localized chest irradiation
with 14 Gy. Treatment with anakinra in irradiated mice significantly reduced Ccl2 and Ccl5 …

… Therapeutic thoracic irradiation may induce two late pulmonary injury syndromes: radiation
… type of radiation-induced lung injury. Alveolar macrophage-derived cytokines, including …

… thoracic irradiation. In 1995, Morgan et al, using both BAL and gallium lung scan, observed
that 75% of women irradiated … in BAL after strictly unilateral thoracic irradiation, even if they …

… factor-β 1 (TGF-β 1 ) or interleukin-6 (IL-6) may serve as a predictor of radiation pneumonitis
6, 7, 8. The influence of thoracic RT on the production of cytokines in the human lung, …

… irradiation compared to non-irradiated ones, regardless of the amount of time between
irradiation … blood serum from irradiated mice given to syngeneic non-irradiated recipients of bone …

… interleukin (IL)-1α, and IL-6 in the lung tissue of C57BL/6 mice after thoracic irradiation with
12 Gy. … In the standard mouse model of single-dose thoracic irradiation, the timing of radiation …

… of thoracic irradiation. To test this hypothesis, studies were undertaken to examine the effects
of IL-11 on mortality from thoracic irradiation and … seen following thoracic irradiation, without …