… cells incubated in the presence or absence of the COX‐2 inhibitor NS398 or IFNγ, with and
without MTX. Foam cell transformation of lipid‐laden THP‐1 … foam cell formation in THP‐1 …

… foam cells, we have performed a subtractive library screening utilizing mRNA isolated from
THP-1 macrophages and foam cells… is highly upregulated in foam cells in response to oxLDL. …

… on THP-1 macrophage To elucidate the mechanisms by which sd-LDL induced macrophage
foam cell … on THP-1 macrophages (Fig.3A and 3B).The expression level of LDL receptor on …

… Inhibition of the NLRP3 inflammasome attenuates THP-1 macrophage foam cell formation
To investigate the role of the NLRP3 inflammasome in THP-1 macrophage foam cell formation…

… Our results revealed that activin-A inhibited foam cell formation of and CE accumulation
in THP-1 Mφs. This downregulation was paralleled by a reduction in cell association and …

… that dividing THP-1 cells and phorbol ester-treated THP-1 cells are capable of forming foam
cells in response to … However, they are restricted in their ability to form foam cells in response …

… foam cell induced by ox-LDL. Therefore, this study aims to establish whether CTRP9 can
inhibit foam cell … autophagy and to determine the potential mechanism of CTRP9 in foam cells. …

… cells, however, is still unclear. In the present study, we used the human cell line THP1. This
human monocytic cell line responds to phorbol ester (PMA) treatment by dramatic changes in …

… effect on ABCA1 and LXR gene expression in human THP-1 macrophage-derived foam
cells, however, incubation of THP-1 derived foam cells with fatty acids led to the reduction of TC, …

… in macrophages transforms them into foam cells, a key element … THP-1 human
monocytes/macrophages, inhibition of COX-1, … THP-1 macrophages showed significantly …